在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PCOLCE Antibody, FITC conjugated

  • 中文名稱:
    PCOLCE兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA614881LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PCOLCE Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PCOLCE
  • 別名:
    PCOC1_HUMAN antibody; Pcolce antibody; PCOLE 1 antibody; PCOLE1 antibody; PCPE antibody; PCPE-1 antibody; PCPE1 antibody; Procollagen C endopeptidase enhancer antibody; Procollagen C-endopeptidase enhancer 1 antibody; Procollagen C-endopeptidase enhancer antibody; Procollagen C-proteinase enhancer 1 antibody; Procollagen COOH-terminal proteinase enhancer 1 antibody; procollagen, type 1, COOH-terminal proteinase enhancer antibody; Type 1 procollagen C-proteinase enhancer protein antibody; Type I procollagen COOH-terminal proteinase enhancer antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Procollagen C-endopeptidase enhancer 1 protein (169-449AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.; C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.
  • 基因功能參考文獻:
    1. Serum PCPE-1 might be used as a noninvasive marker of liver fibrosis in chronic hepatitis B. PMID: 29683980
    2. Results suggest that PCPE-1 binding to syndecans and/or fibronectin may control collagen fibril assembly on the cell surface. PMID: 25286301
    3. The analysis of the PCPE-1 interaction network based on Gene Ontology terms suggests that, besides its role in collagen deposition, PCPE-1 might be involved in tumour growth, neurodegenerative diseases and angiogenesis. PMID: 24117177
    4. The results of this study suggested that nuclear entrapment of PCOLCE and its extracellular depletion represents a novel molecular mechanism in late-onset muscle fibrosis. PMID: 23815790
    5. Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation. PMID: 23550162
    6. data generated by our system, support our hypothesis that combined data on PCPE concentration and isoforms may be useful for the diagnosis and follow-up of bone diseases PMID: 21569766
    7. Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only. PMID: 21940633
    8. procollagen C-proteinase enhancer-1 (PCPE-1) binds to heparin/heparan sulfate and has a role in interaction with cells PMID: 20729553
    9. Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity. PMID: 20207734
    10. Data show that only those containing both PCPE1 CUB1 and CUB2 were capable of enhancing BMP-1 activity and binding to a mini-procollagen substrate with nanomolar affinity. PMID: 19801683
    11. PCPE binds to sites on either side of the procollagen cleavage site, thereby facilitating the action of procollagen C-proteinases. PMID: 12105202
    12. PCPE1 and PCPE2 were found to be collagen-binding proteins, capable of binding at multiple sites on the triple helical portions of fibrillar collagens and also capable of competing for such binding with procollagen C-proteinases PMID: 12393877
    13. procollagen C-proteinase enhancer is an elongated multidomain glycoprotein as shown by small angle x-ray scattering PMID: 12486138
    14. the three-dimensional structure of the NTR domain of human PCOLCE1 is the first example of a structural domain with the canonical features of an NTR module PMID: 12670942
    15. chordinase activity of BMP1 is not enhanced by PCPE-1 PMID: 15817489
    16. tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains PMID: 16507574
    17. PCPE-stimulating activity requires a calcium binding motif in the CUB1 domain that is highly conserved among CUB-containing proteins PMID: 17446170
    18. in bone fracture patients, 12 proteins were related to bone/cartilage metabolism, including: TGF-beta induced protein IG-H(3), cartilage acidic protein 1, procollagen C proteinase enhancer protein and TGF-beta receptor III. PMID: 17602227
    19. PCPE-1 interacts with beta2-microglobulin (beta2-m) and may help initiate beta2-m amyloid fibril formation in connective tissues PMID: 18164932
    20. Procollagen I mRNA expression was decreased by synovial fluid from patients with prosthesis loosening. PMID: 18350290
    21. the sPCPE1 glycopattern appears to be associated with the physiological and pathological states of bone PMID: 19361460

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 數據庫鏈接:

    HGNC: 8738

    OMIM: 600270

    KEGG: hsa:5118

    STRING: 9606.ENSP00000223061

    UniGene: Hs.202097



主站蜘蛛池模板: 国产无套粉嫩白浆在线观看| 捆绑白丝粉色jk震动捧喷白浆| 亚洲 欧美精品suv| 日韩精品久久久久久免费| 欧美日韩亚洲中文字幕一区二区三区| 国产偷国产偷亚洲高清日韩| 蜜臀av一区二区| 国产美女裸体丝袜喷水视频 | 精品视频无码一区二区三区| 欧美制服丝袜人妻另类| 一区二三区在线 | 中国| 久久人妻av无码中文专区| 在线观看国产精品电影| 国产在线欧美日韩精品一区 | 无翼乌工口全彩肉肉无遮挡18| 国产 日韩 另类 视频一区| 九九综合va免费看| 国产日产亚洲系列最新| 又色又污又爽又黄的网站| 55夜色66夜色国产精品视频| 国产精品人妻久久久久| 人妻色综合网站| 一本色道无码道在线观看| 久热中文字幕无码视频| 欧美午夜精品一区二区蜜桃| 欧美性大战久久久久久| 欧美成人精品三级一二三在线观看| 少妇熟女久久综合网色欲| 亚洲精品中国国产嫩草影院美女| 熟女人妻大叫粗大受不了| 天天看片视频免费观看| 中文字幕免费无码专区| 热99re久久精品这里都是精品| 亚洲欧美国产精品久久久久久久| 久久视频这里有精品33| 亚洲午夜久久久无码精品网红a片| 国内精品久久久久久tv| 国产亚洲色婷婷久久99精品| 亚洲顶级裸体av片| 国产一区二区三精品久久久无广告| 国产97在线 | 免费|