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  4. PAXBP1 Antibody

PAXBP1 Antibody

  • 中文名稱：
    PAXBP1兔多克隆抗體
  • 貨號：
    CSB-PA003778GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PAXBP1
  • 別名：
    BM 020 antibody; BM020 antibody; Chromosome 21 open reading frame 66 antibody; FSAP105 antibody; Functional spliceosome-associated protein 105 antibody; GC rich sequence DNA binding factor candidate antibody; GC-rich sequence DNA-binding factor 1 antibody; GCFC antibody; GCFC1 antibody; GCFC1_HUMAN antibody; PAX3 and PAX7 binding protein 1 antibody; PAXBP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human C21orf66
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20.
  • 基因功能參考文獻：
    1. A homozygous potentially pathogenic variant in the PAXBP1 gene in a large family with global developmental delay and myopathic hypotonia has been reported. PMID: 28542722
    2. The GCFC1/C21orf66 distal promoter contains an inhibitory cis-regulatory element that is responsive to Trichostatin A (TSA) treatment according to promoter reporter assays in HEK 293 cells. PMID: 20494980
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    GCF family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 13579

    OMIM: 617621

    KEGG: hsa:94104

    STRING: 9606.ENSP00000328992

    UniGene: Hs.644004



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