在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PARG Antibody

  • 中文名稱:
    PARG兔多克隆抗體
  • 貨號:
    CSB-PA773045LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunofluorescent analysis of PC-3 cells using CSB-PA773045LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PARG Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    ADP riboseglycohydrolase antibody; Mitochondrial poly(ADP ribose) glycohydrolase antibody; Parg antibody; PARG_HUMAN antibody; PARG99 antibody; Poly antibody; poly (ADP ribose) glycohydrolase antibody; poly(ADP-ribose) glycohydrolase 60 kDa isoform antibody; Poly(ADP-ribose) glycohydrolase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Poly(ADP-ribose) glycohydrolase protein (1-348AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,PARG Antibody (CSB-PA773045LA01HU),的標記方式是Non-conjugated。對于PARG Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA773045LB01HU PARG Antibody, HRP conjugated ELISA
    FITC CSB-PA773045LC01HU PARG Antibody, FITC conjugated
    Biotin CSB-PA773045LD01HU PARG Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Poly(ADP-ribose) glycohydrolase that degrades poly(ADP-ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-ribose monomers. It is however unable to cleave the ester bond between the terminal ADP-ribose and ADP-ribosylated residues, leaving proteins that are mono-ADP-ribosylated. Poly(ADP-ribose) is synthesized after DNA damage is only present transiently and is rapidly degraded by PARG. Required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress, while it is not required for recovery from transient replicative stress. Responsible for the prevalence of mono-ADP-ribosylated proteins in cells, thanks to its ability to degrade poly(ADP-ribose) without cleaving the terminal protein-ribose bond. Required for retinoid acid-dependent gene transactivation, probably by removing poly(ADP-ribose) from histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters. Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.
  • 基因功能參考文獻:
    1. The catalytic efficiency (kcat/Km) of rBPHL for homocysteine thiolactone hydrolysis was 7.7 x 10(4) M(-1)s(-1), orders of magnitude higher than that of PON1 or Blmh, indicating a more significant physiological role for BPHL in detoxifying HCTL PMID: 25333274
    2. BPHL catalyzes the hydrolytic activation of the antiviral prodrugs valacyclovir and valganciclovir. PMID: 15832508
    3. BPHL is a serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nuceloside analogs such as valacyclovir and valganciclovir. PMID: 12732646
  • 亞細胞定位:
    [Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm. Mitochondrion.; [Isoform 5]: Mitochondrion matrix.
  • 蛋白家族:
    Poly(ADP-ribose) glycohydrolase family
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 8605

    OMIM: 603501

    KEGG: hsa:8505

    STRING: 9606.ENSP00000384408

    UniGene: Hs.10136



主站蜘蛛池模板: 被窝影院午夜无码国产| 久久久久人妻精品一区蜜桃| 99精品国产再热久久无毒不卡| 337p粉嫩日本欧洲亚福利 | 成人毛片无码免费播放网站| 亚洲高请码在线精品av| 中文无码av在线亚洲电影| 美女大量吞精在线观看456| 亚洲色欲久久久久综合网| 欧美乱码伦视频免费| 少妇激情作爱视频| 无码成人一区二区| 久久亚洲精品中文字幕| 久久视频这里只精品99| 女人被爽到高潮视频免费国产 | 亚洲日韩精品欧美一区二区一| 国内精品久久久久影院嫩草| 欧美精品1卡二卡三卡四卡| 熟妇五十路六十路息与子| www国产精品内射老师| 国产av久久人人澡人人爱| 国产肉丝袜视频在线观看| 欧美 日韩 国产 亚洲 色| 国产精品99久久久久久www| 亚洲中文有码字幕日本第一页| 国产精品系列无码专区| 午夜精品久久久久久久| 天堂а√在线官网| 亚洲国产制服丝袜先锋| 无码免费一区二区三区| 美女内射视频www网站午夜| 亚洲午夜成人精品无码app| 久久久久久人妻精品一区| 57pao成人国产永久免费视频| 国产成人精品午夜福利在线播放| 少妇久久久久久人妻无码| 一区二区在线 | 欧洲| 色欲精品国产一区二区三区av| 疯狂迎合进入强壮公的视频| 亚洲午夜无码久久| 无码国产精品一区二区免费虚拟vr|