在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PARD6B Antibody

  • 中文名稱:
    PARD6B兔多克隆抗體
  • 貨號:
    CSB-PA070032
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    PARD6B antibody; PAR6BPartitioning defective 6 homolog beta antibody; PAR-6 beta antibody; PAR-6B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human PAR-6β.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
  • 基因功能參考文獻:
    1. found that the polarity determinants Cdc42, Par6B, PKCzeta/iota and the structural proteins ezrin and phospho-ezrin were lost from the apical membrane and accumulated either in the cytoplasm or on the basal side of enterocytes in patients PMID: 26526116
    2. PAK4 phosphorylates Par6B at Ser143 blocking its interaction with Cdc42. PMID: 25662318
    3. Data conclude that Par6B and aPKC control mitotic spindle orientation in polarized epithelia and, furthermore, that aPKC coordinately regulates multiple processes to promote morphogenesis. PMID: 21300793
    4. This study demonstrates that controlled regulation of PAK4 is required for apical junction formation in lung epithelial cells and highlights potential cross-talk between two Cdc42 targets, PAK4 and Par6B. PMID: 20631255
    5. The ability of SRC family coactivators to regulate the expression of one of these genes, PARD6B/Par6, was confirmed by using cells individually depleted of SRC-1. PMID: 15677324
    6. Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. PMID: 19401335

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cell membrane. Cell junction, tight junction.
  • 蛋白家族:
    PAR6 family
  • 組織特異性:
    Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
  • 數據庫鏈接:

    HGNC: 16245

    OMIM: 608975

    KEGG: hsa:84612

    STRING: 9606.ENSP00000360672

    UniGene: Hs.589848



主站蜘蛛池模板: 亚洲精品无码久久久久av麻豆| 成人乱人伦视频在线观看| 亚洲精品一区二区丝袜图片| 亚洲成a人v电影在线观看| 牲交欧美兽交欧美| 久人人爽人人爽人人片av| 男女野外做爰全过程69影院| 最近日本mv字幕免费高清完整版| 朝鲜女子内射杂交bbw| 亚洲国产一区二区三区波多野结衣| 国产xxxx做受性欧美88| 中文亚洲无线码49vv| 激情97综合亚洲色婷婷五| 国产狂喷潮在线观看中文| 久久午夜夜伦鲁鲁片免费无码| www亚洲精品久久久| 国精品99久9在线 | 免费| 制服丝袜另类专区制服| 伊人www22综合色| 无码少妇一区二区浪潮免费| 曰批全过程免费视频观看软件潮喷| 午夜不卡av免费| 99e久热只有精品8在线直播| 欧美性狂猛xxxxx深喉| 中文字幕乱码熟妇五十中出色欲| 67194成是人免费无码| 亚洲日韩av一区二区三区中文| 国产在线看片免费视频| 老子影院午夜伦手机不四虎卡 | 久久丫精品久久丫| 伊人成年网站综合网| 日本japanese丰满多毛| 最近2019免费中文第一页| 国产熟睡乱子伦视频| a毛看片免费观看视频| 成人网站国产在线视频内射视频 | 亚洲天天做日日做天天谢日日欢| 亚洲欧洲美洲无码精品va| 久久精品成人免费观看| 伊人久久大香线蕉无码| 国产激情无码一区二区|