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PAK6 Antibody

  • 中文名稱：
    PAK6兔多克隆抗體
  • 貨號：
    CSB-PA865108ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA865108ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA865108ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PAK6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PAK6
  • 別名：
    CDKN1A activated kinase 6 antibody; EC 2.7.1.37 antibody; p21 activated protein kinase 6 antibody; p21 protein (Cdc42/Rac)-activated kinase 6 antibody; p21(CDKN1A) activated kinase 6 antibody; p21-activated kinase 6 antibody; p21activated kinase 6 antibody; PAK 5 antibody; PAK 6 antibody; PAK-5 antibody; PAK-6 antibody; PAK5 antibody; Pak6 antibody; PAK6_HUMAN antibody; Serine threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK6 antibody; Serine/threonine-protein kinase PAK 6 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein kinase PAK 6 protein (1-270AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=Cotranslocates into nucleus with AR in response to androgen induction.
  • 蛋白家族：
    Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
  • 組織特異性：
    Selectively expressed in brain and testis, with lower levels in multiple tissues including prostate and breast.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16061

    OMIM: 608110

    KEGG: hsa:106821730

    STRING: 9606.ENSP00000260404

    UniGene: Hs.732375



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