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  4. PAFAH1B3 Antibody

PAFAH1B3 Antibody

  • 中文名稱：
    PAFAH1B3兔多克隆抗體
  • 貨號：
    CSB-PA017385GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PAFAH1B3
  • 別名：
    PA1B3_HUMAN antibody; PAF acetylhydrolase 29 kDa subunit antibody; PAF AH 29 kDa subunit antibody; PAF AH subunit gamma antibody; PAF-AH 29 kDa subunit antibody; PAF-AH subunit gamma antibody; PAFAH subunit gamma antibody; Pafah1b3 antibody; PAFAHG antibody; Platelet activating factor acetylhydrolase IB subunit gamma antibody; Platelet activating factor acetylhydrolase isoform Ib gamma subunit (29kD) antibody; Platelet activating factor acetylhydrolase isoform Ib gamma subunit 29kDa antibody; Platelet activating factor acetylhydrolase isoform Ib gamma subunit antibody; Platelet-activating factor acetylhydrolase IB subunit gamma antibody
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PAFAH1B3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Alpha1 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF. The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition. Both alpha1/alpha1 homodimer (PAFAH1B3/PAFAH1B3 homodimer) and alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B2 heterodimer) hydrolyze 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA) more efficiently than PAF, but they have little hydrolytic activity towards 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE). Plays an important role during the development of brain.
  • 基因功能參考文獻：
    1. PAFAH1B3 as a critical metabolic node in breast cancer PMID: 24954006
    2. PAFAH1B3 has been found to be differentially methylated in head and neck squamous cell carcinoma. PMID: 22461910
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    'GDSL' lipolytic enzyme family, Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily
  • 組織特異性：
    In the adult, expressed in brain, skeletal muscle, kidney, thymus, spleen, colon, testis, ovary and peripheral blood leukocytes. In the fetus, highest expression occurs in brain.
  • 數據庫鏈接：

    HGNC: 8576

    OMIM: 603074

    KEGG: hsa:5050

    STRING: 9606.ENSP00000262890

    UniGene: Hs.466831



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