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PAB2 Antibody

  • 中文名稱：
    PAB2 Antibody
  • 貨號(hào)：
    CSB-PA017365XA01DOA
  • 規(guī)格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:PAB2 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 35.5 kDa
      Observed band size: 35 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Arabidopsis thaliana PAB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PAB2
  • 別名：
    Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) PAB2 At4g34110 F28A23.130
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Arabidopsis thaliana
  • 免疫原：
    Recombinant Arabidopsis thaliana PAB2 protein (36-292aa)
  • 免疫原種屬：
    Arabidopsis thaliana
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Stimulates translation by interaction with translation initiation factor eIF4G, a subunit of the cap-binding complex eIF4F, bringing the 5'- and 3'-ends of the mRNA in proximity. The formation of this circular mRNP structure appears to be critical for the synergistic effects of the cap and the poly(A) tail in facilitating translation initiation, recycling of ribosomes, and mRNA stability. During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp).
  • 基因功能參考文獻(xiàn)：
    1. Poly(A) Binding Protein binds to uridylated oligo(A) tails and determines the length of U-extensions added by URT1. PMID: 26972004
    2. PAB2 was partially retargeted to the nucleolus in the presence of TuMV VPg-Pro. In addition, the membrane association of PAB2 during TuMV infection resulted from the internalization of the host protein in 6K-VPg-Pro-induced vesicles. PMID: 17670821
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Note=In TuMV-infected plants, partially retargeted in cytoplasmic virus-induced vesicles and in the nucleolus.
  • 蛋白家族：
    Polyadenylate-binding protein type-1 family
  • 組織特異性：
    Expressed in all organs (at the protein level) but under distinct spatial and temporal regulation within each organ.
  • 數(shù)據(jù)庫鏈接：

    KEGG: ath:AT4G34110

    STRING: 3702.AT4G34110.1

    UniGene: At.25252



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