在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. P4HA2 Antibody

P4HA2 Antibody

  • 中文名稱：
    P4HA2兔多克隆抗體
  • 貨號：
    CSB-PA017340ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA017340ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA017340ESR2HU at dilution of 1:100
    • Immunoprecipitating P4HA2 in Hela whole cell lysate
      Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA017340ESR2HU in Hela whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
      Lane 2: CSB-PA017340ESR2HU (4μg) + Hela whole cell lysate (500μg)
      Lane 3: Hela whole cell lysate (20μg)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) P4HA2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    2-oxoglutarate-4-dioxygenase subunit alpha-2 antibody; 4 PH alpha 2 antibody; 4-PH alpha-2 antibody; C-P4Halpha(II) antibody; collagen prolyl 4-hydroxylase alpha(II) antibody; P4HA2 antibody; P4HA2_HUMAN antibody; procollagen proline, 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase), alpha polypeptide II antibody; procollagen proline, 2 oxoglutarate 4 dioxygenase alpha subunit, isoform 2 antibody; Procollagen-proline antibody; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2 antibody; Prolyl 4 hydroxylase alpha 2 subunit antibody; Prolyl 4 hydroxylase subunit alpha 2 [Precursor] antibody; Prolyl 4-hydroxylase subunit alpha-2 antibody; Prolyl 4-hydroxylase, alpha polypeptide II antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Prolyl 4-hydroxylase subunit alpha-2 protein (236-535AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IP
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
  • 基因功能參考文獻：
    1. Assembly of the elongated collagen prolyl 4-hydroxylase alpha2beta2 heterotetramer around a central alapha2 dimer has been reported. PMID: 28093469
    2. Plasminogen and P4HA2 are involved in vascular remodelling and angiogenesis, suggesting a high relevance of these processes for the pathogenic mechanisms underlying this type of vasculitis PMID: 28041642
    3. RNAsequencing showed that the t(4;5)(q24;q31) resulted in recombination of the genes TBCK on 4q24 and P4HA2 on 5q31.1 with generation of an inframe TBCKP4HA2 and the reciprocal but outofframe P4HA2TBCK fusion transcripts. PMID: 27633981
    4. P4HA2 was identified as a novel causative gene for nonsyndromic high myopia. PMID: 25741866
    5. Suggest the critical role of P4HA2 in breast cancer progression and identify P4HA2 as a potential therapeutic target and biomarker for breast cancer progression. PMID: 24383403
    6. Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts. PMID: 23423382
    7. P4HA2 was upregulated in breast tumor cells compared with its adjacent normal tissues. PMID: 22813596
    8. Overexpression of PRDX4 and P4HA2 was significantly associated with lymphatic metastasis in oral cavity squamous cell carcinoma PMID: 21859152
    9. the substrate specificity, binding site and conformation of this enzyme PMID: 12824157
    10. In comparison with healthy cartilage, Osteoarthritis articular chondrocytes exhibit increased in vivo synthesis of collagen prolyl-4-hydroxylase type II, a pivotal enzyme in collagen triple helix formation. PMID: 16877351
    11. HIF-P4H, HIF-1alpha and HIF-2alpha are effective oxygen sensors PMID: 16885164
    12. results show that p53 transcriptionally activates the alpha(II) collagen prolyl-4-hydroxylase [alpha(II)PH] gene, resulting in the extracellular release of antiangiogenic fragments of collagen type 4 and 18 PMID: 16917063

    顯示更多

    收起更多

  • 相關疾病：
    Myopia 25, autosomal dominant (MYP25)
  • 亞細胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    P4HA family
  • 數據庫鏈接：

    HGNC: 8547

    OMIM: 600608

    KEGG: hsa:8974

    STRING: 9606.ENSP00000166534

    UniGene: Hs.519568



主站蜘蛛池模板： 成人毛片一区二区| 色先锋资源久久综合5566| 女人被狂躁到高潮视频免费软件| 亚洲乱亚洲乱妇无码| 老色鬼永久视频网站| 性欧美丰满熟妇xxxx性5| 国产综合18久久久久久| 欧美毛多水多肥妇| 亚洲精品国产suv一区88| 99精品一区二区三区无码吞精 | 欧美高清freexxxx性| 中文字幕人妻无码专区| 成年网站未满十八禁视频天堂 | 久久亚洲日韩精品一区二区三区 | 人人妻人人玩人人澡人人爽| 免费国精产品—品二品| 天天拍夜夜添久久精品| 欧美成人精品午夜免费影视| 国产卡一卡二无线乱码| 丰满人妻翻云覆雨呻吟视频| 我和亲妺妺乱的性视频| 久99久热只有精品国产女同| 青青青国产在线观看免费| 蜜柚av久久久久久久| 性一交一黄一片| 美女黄18以下禁止观看| 亚洲va久久久噜噜噜久久男同| 国产成+人欧美+综合在线观看 | 精品人妻系列无码人妻漫画| 激情综合色综合久久综合| 天天摸夜夜添狠狠添高潮出水| 2023国产精品一卡2卡三卡4卡 | 国产精品无码av天天爽| 久久青青草原国产精品最新片 | 在线观看欧美一区二区三区| 久久精品国产欧美日韩99热| 亚洲国产成人无码电影| 久久偷看各类wc女厕嘘嘘偷窃| 高潮毛片无遮挡高清视频播放| 337p日本欧洲亚洲大胆艺术图| 国产亚洲精品影视在线|