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  4. OTUB2 Antibody

OTUB2 Antibody

  • 中文名稱：
    OTUB2兔多克隆抗體
  • 貨號：
    CSB-PA003604
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Colo205 cells using OTUB2 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    C14orf137 antibody; Deubiquitinating enzyme OTUB2 antibody; FLJ21916 antibody; MGC3102 antibody; OTB2 antibody; OTU domain containing ubiquitin aldehyde binding protein 2 antibody; OTU domain, ubiquitin aldehyde binding 2 antibody; OTU domain-containing ubiquitin aldehyde-binding protein 2 antibody; OTU2 antibody; Otub2 antibody; OTUB2_HUMAN antibody; Otubain 2 antibody; Otubain-2 antibody; Ubiquitin specific processing protease OTUB2 antibody; Ubiquitin specific protease otubain 2 antibody; Ubiquitin thioesterase OTUB2 antibody; Ubiquitin-specific-processing protease OTUB2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human OTUB2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.
  • 基因功能參考文獻：
    1. OTUB2 fine-tunes the speed of double-strand break-induced ubiquitination so that the appropriate DNA repair pathway is chosen PMID: 24560272
    2. OTUB2 is a novel promoter of viability and insulin secretion in human beta cells. OTUB2 acts through the inhibition of NF-kappaB signalling. PMID: 23515685
    3. Data report the first crystal structure of an OTU superfamily protein, otubain 2, at 2.1 A resolution and propose a model for otubain-ubiquitin binding. PMID: 15258613
  • 蛋白家族：
    Peptidase C65 family
  • 組織特異性：
    Widely expressed. Expressed at higher level in brain.
  • 數據庫鏈接：

    HGNC: 20351

    OMIM: 608338

    KEGG: hsa:78990

    STRING: 9606.ENSP00000203664

    UniGene: Hs.278815



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