在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

OPN5 Antibody, Biotin conjugated

  • 中文名稱:
    OPN5兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA740895LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) OPN5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    OPN5; GPR136; PGR12; TMEM13; Opsin-5; G-protein coupled receptor 136; G-protein coupled receptor PGR12; Neuropsin; Transmembrane protein 13
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Opsin-5 protein (310-353AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    G-protein coupled receptor which selectively activates G(i) type G proteins via ultraviolet A (UVA) light-mediated activation in the retina. Preferentially binds the chromophore 11-cis retinal and is a bistable protein that displays emission peaks at 380 nm (UVA light) and 470 nm (blue light). Required for the light-response in the inner plexiform layer, and contributes to the regulation of the light-response in the nerve fiber layer, via phosphorylated DAT/SLC6A3 dopamine uptake. Involved in local corneal and retinal circadian rhythm photoentrainment via modulation of the UVA light-induced phase-shift of the retina clock. Acts as a circadian photoreceptor in the outer ear, via modulation of circadian clock-gene expression in response to violet light during the light-to-dark transition phase and night phase of the circadian cycle. Required in the retina to negatively regulate hyaloid vessel regression during postnatal development via light-dependent OPN5-SLC32A1-DRD2-VEGFR2 signaling. Involved in the light-dependent regulation of retina and vitreous compartment dopamine levels.
  • 基因功能參考文獻:
    1. Expression of the hNP gene on the mRNA level, evaluated based on peripheral blood, is significantly higher in the patients with MRD than in the healthy subjects. PMID: 28636578
    2. Data indicate that opsin5 (OPN5) photoreceptor mediates light-induced Ca(2+) response. PMID: 24941910
    3. It dissects a schizophrenic susceptibility gene, NRG1. PMID: 24614639
    4. Opn5m may work exclusively as a short wavelength sensor in the brain as well as in the retina with the assistance of an 11-cis-retinal-supplying system. PMID: 24403072
    5. UV photoreceptor in human beings OPN5 triggers a UV-sensitive Gi-mediated signaling pathway in the mammalian tissues. PMID: 22043319
    6. Genetic variation of the hNP gene may contribute to molecular mechanisms of bipolar disorder and some aspects of memory and intelligence. PMID: 18354391

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family, Opsin subfamily
  • 組織特異性:
    Detected in brain and retina and cell lines derived from neural retina.
  • 數據庫鏈接:

    HGNC: 19992

    OMIM: 609042

    KEGG: hsa:221391

    STRING: 9606.ENSP00000360255

    UniGene: Hs.213717



主站蜘蛛池模板: 无码av中文一区二区三区 | 亚洲天堂2017无码中文| 久久精品国产亚洲欧美| 无码人妻精品一区二区三区下载| 国产精品久久久久久久久久红粉| 欧美成人看片一区二区三区尤物| 国产亚洲精品久久久性色情软件| 欧美乱人伦视频在线| 黑人大荫道bbwbbb高潮潮喷| 伊人激情av一区二区三区| 亚洲aⅴ无码专区在线观看| 无码人妻丝袜在线视频红杏| 亚洲人成人网站在线观看| 日本三级欧美三级人妇视频黑白配| 亚洲精品国产精华液有哪些| 欧美老肥熟妇多毛xxxxx| 欧美午夜精品一区二区蜜桃| 亚洲成av人片一区二区密柚| 久久久青草青草免费看| 永久免费观看美女裸体视频的网站| 欧美成人片一区二区三区| 久久综合亚洲色hezyo国产| 2020国产亚洲美女精品久久久 | 欧美极品少妇无套实战| 爆爽久久久一区二区又大又黄又嫩 | 色偷偷女人的天堂亚洲网| 中文无码vr最新无码av专区| 久久中文字幕人妻av熟女| 免费人成网站视频在线观看| 少妇无码一区二区三区免费| 肥臀浪妇太爽了快点再快点| 日本熟妇人妻xxxxx-欢迎您| 中文无码日韩欧免费视频| 永久黄网站色视频免费| 98久久人妻少妇激情啪啪| 午夜男女无遮挡拍拍视频| 国产av偷闻女邻居内裤被发现| 久久久久久久久久久久久9999 | 午夜福利体验免费体验区| 在线观看国产丝袜控网站| 久久伊人蜜桃av一区二区|