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  4. OPLAH Antibody

OPLAH Antibody

  • 中文名稱：
    OPLAH兔多克隆抗體
  • 貨號：
    CSB-PA016350GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    OPLAH
  • 別名：
    5 Opase antibody; 5 oxo L prolinase antibody; 5 oxoprolinase (ATP hydrolysing) antibody; 5 oxoprolinase antibody; 5-OPase antibody; 5-oxo-L-prolinase antibody; 5-oxoprolinase antibody; DKFZp434H244 antibody; OPLA antibody; OPLA_HUMAN antibody; oplah antibody; OPLAHD antibody; Pyroglutamase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human OPLAH
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  • 基因功能參考文獻：
    1. An autosomal recessive mode of inheritance for 5-oxoprolinase deficiency is further supported by the identification of a single mutation in all 9/14 parent sample sets investigated (except for the father of one patient whose result suggests homozygosity), and the absence of 5-oxoprolinuria in all tested heterozygotes PMID: 27477828
    2. In this study, clinical, biochemical, and genetic aspects of five Chinese 5-oxoprolinuria patients with OPLAH or GSS gene mutations were investigated. PMID: 25851806
    3. the cause of cellular ATP depletion in nephrotic cystinosis may be the futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase PMID: 20413906
  • 相關(guān)疾病：
    5-oxoprolinase deficiency (OPLAHD)
  • 蛋白家族：
    Oxoprolinase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8149

    OMIM: 260005

    KEGG: hsa:26873

    UniGene: Hs.305882



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