在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. OPA3 Antibody

OPA3 Antibody

  • 中文名稱：
    OPA3兔多克隆抗體
  • 貨號：
    CSB-PA880985ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: OPA3 antibody at 4.91 μg/ml + Mouse eye tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 20, 21 kDa
      Observed band size: 20 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA880985ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA880985ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) OPA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    OPA3
  • 別名：
    OPA3 antibody; Optic atrophy 3 protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Optic atrophy 3 protein (25-179AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play some role in mitochondrial processes.
  • 基因功能參考文獻：
    1. Mutations of the OPA3 gene can cause either autosomal dominant or autosomal recessive optic atrophy. PMID: 25205859
    2. Report the results of a comprehensive study on OPA3 mutations, including the mutation spectrum and its prevalence in a large cohort of ADOA patients, the associated clinical phenotype and the functional characterisation of a newly identified OPA3 mutant. PMID: 24136862
    3. A novel missense mutation identifies OPA3 as the cause of a complex neurological disorder with marked lower limb dystonia. PMID: 23700088
    4. OPA1 mutations are the most common genetic defects identified in patients with suspected Autosomal-dominant optic atrophy (DOA), whereas OPA3 mutations are very rare in isolated optic atrophy cases. PMID: 21036400
    5. OPA3, as an integral mitochondrial outer membane perotein, has a crucial role in mitochondrial fission, and provides a direct link between mitochondrial morphology and optic atrophy. PMID: 20372962
    6. findings thus place the cellular metabolic defect of 3-methylglutaconic aciduria type III in the mitochondrion rather than the peroxisome and implicate loss of OPA3A rather than gain of OPA3B in disease etiology. PMID: 20350831
    7. two missense mutations in OPA3 in two families affected by autosomal dominant optic atrophy and cataract (ADOAC) PMID: 15342707
    8. patient with Costeff syndrome presenting the characteristics of this syndrome and the single-nucleotide polymorphic gene that causes this disease. PMID: 16838891
    9. OPA1 mutations, mtDNA mutations, and OPA3 mutations in 980 patients Leber's hereditary optic neuropathy and autosomal dominant optic atrophy PMID: 19319978
    10. The mouse ortholog of OPA3 purifies with mitochondrial inner membranes. PMID: 12865426
    11. The mouse ortholog of OPA3 purifies with mitochondria PMID: 18614015
    12. type III 3-methylglutaconic aciduria (optic atrophy plus syndrome, or Costeff optic atrophy syndrome): identification of the OPA3 gene and its founder mutation in Iraqi Jews PMID: 11668429

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    3-methylglutaconic aciduria 3 (MGA3); Optic atrophy 3 (OPA3)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    OPA3 family
  • 組織特異性：
    Ubiquitous. Most prominent expression in skeletal muscle and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8142

    OMIM: 165300

    KEGG: hsa:80207

    UniGene: Hs.466945



主站蜘蛛池模板： 欧美日韩人妻精品一区二区在线| 国产9色在线 | 日韩| 国产另类ts人妖一区二区| 久久精品成人免费国产| 2020久久超碰国产精品最新| 欧精国精产品一区| 亚洲五月综合缴情在线| 在线综合亚洲欧洲综合网站| 俄罗斯少妇性xxxx另类| 无码专区久久综合久中文字幕| 国产精品老热丝在线观看| 国内大量揄拍人妻精品視頻 | 无码潮喷a片无码高潮视频| 亚洲中文字幕无码久久精品1| 欧美变态暴力牲交videos| 中文字幕乱码一区二区免费| 一二三四在线视频观看社区| 成人精品一区二区三区中文字幕| 无码国内精品久久人妻蜜桃| 2020国产精品午夜福利在线观看| 国产精品后入内射日本在线观看| 自慰系列无码专区| 久久99精品久久久久久2021| 国产精品丰臀| 久久久www成人免费毛片| 国产精品女主播主要上线| 久久久久久夜精品精品免费啦 | 99热精品国自产拍天天拍| 伊人久久大香线蕉综合中文字幕| 午夜不卡久久精品无码免费| 国产免费人成视频尤勿视频| 亚洲国产成人综合在线不卡| 蜜桃臀无码内射一区二区三区| 蜜桃成人无码区免费视频网站| 免费无码又爽又刺激软件下载| 国产午夜福利久久精品| 日本大片免a费观看视频三区| 日本中文字幕乱码aa高清电影 | 久久精品国产69国产精品亚洲| 少妇愉情理伦片丰满丰满午夜| 国产成人精品一区二区不卡|