在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. OPA3 Antibody

OPA3 Antibody

  • 中文名稱：
    OPA3兔多克隆抗體
  • 貨號：
    CSB-PA880985ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: OPA3 antibody at 4.91 μg/ml + Mouse eye tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 20, 21 kDa
      Observed band size: 20 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA880985ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA880985ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) OPA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    OPA3
  • 別名：
    OPA3 antibody; Optic atrophy 3 protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Optic atrophy 3 protein (25-179AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play some role in mitochondrial processes.
  • 基因功能參考文獻：
    1. Mutations of the OPA3 gene can cause either autosomal dominant or autosomal recessive optic atrophy. PMID: 25205859
    2. Report the results of a comprehensive study on OPA3 mutations, including the mutation spectrum and its prevalence in a large cohort of ADOA patients, the associated clinical phenotype and the functional characterisation of a newly identified OPA3 mutant. PMID: 24136862
    3. A novel missense mutation identifies OPA3 as the cause of a complex neurological disorder with marked lower limb dystonia. PMID: 23700088
    4. OPA1 mutations are the most common genetic defects identified in patients with suspected Autosomal-dominant optic atrophy (DOA), whereas OPA3 mutations are very rare in isolated optic atrophy cases. PMID: 21036400
    5. OPA3, as an integral mitochondrial outer membane perotein, has a crucial role in mitochondrial fission, and provides a direct link between mitochondrial morphology and optic atrophy. PMID: 20372962
    6. findings thus place the cellular metabolic defect of 3-methylglutaconic aciduria type III in the mitochondrion rather than the peroxisome and implicate loss of OPA3A rather than gain of OPA3B in disease etiology. PMID: 20350831
    7. two missense mutations in OPA3 in two families affected by autosomal dominant optic atrophy and cataract (ADOAC) PMID: 15342707
    8. patient with Costeff syndrome presenting the characteristics of this syndrome and the single-nucleotide polymorphic gene that causes this disease. PMID: 16838891
    9. OPA1 mutations, mtDNA mutations, and OPA3 mutations in 980 patients Leber's hereditary optic neuropathy and autosomal dominant optic atrophy PMID: 19319978
    10. The mouse ortholog of OPA3 purifies with mitochondrial inner membranes. PMID: 12865426
    11. The mouse ortholog of OPA3 purifies with mitochondria PMID: 18614015
    12. type III 3-methylglutaconic aciduria (optic atrophy plus syndrome, or Costeff optic atrophy syndrome): identification of the OPA3 gene and its founder mutation in Iraqi Jews PMID: 11668429

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    3-methylglutaconic aciduria 3 (MGA3); Optic atrophy 3 (OPA3)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    OPA3 family
  • 組織特異性：
    Ubiquitous. Most prominent expression in skeletal muscle and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8142

    OMIM: 165300

    KEGG: hsa:80207

    UniGene: Hs.466945



主站蜘蛛池模板： 一本大道av伊人久久综合| 和黑人邻居中文字幕在线| 一边吃奶一边摸做爽视频| 亚洲欧美日韩精品久久亚洲区| 欧美黑人与白人精品a片| 国内精品久久久久久影院| 青乐娱精品视频一国产分类| 久艾草在线精品视频在线观看| 国产乱人伦精品一区二区在线观看| 亚洲国产精品无码一线岛国| 樱花草在线社区www中国中文 | 国产一卡2卡3卡四卡精品国色无边 | 天天躁日日躁狠狠躁性色av| 伊人久久大香线蕉综合中文字幕| 色婷婷av99xx| 午夜福利体验免费体验区| 成人免费网站视频www| 亚洲欧洲国产成人综合在线观看 | 熟睡人妻被讨厌的公侵犯| 久久久精品2020免费观看| 国产精品一区二区av片| 国产v在线在线观看视频免费| 爆乳熟妇一区二区三区霸乳| 69久久国产露脸精品国产| 麻豆国产成人av在线播放欲色 | 日日碰狠狠添天天爽无码| 十八18禁国产精品www| 在线观看一区二区三区国产免费| 国产成人免费高清直播| 丰满少妇熟乱xxxxx视频| 好吊妞无缓冲视频观看| 最新亚洲伦理中文字幕| 人人摸人人搞人人透| 欧美国产国产综合视频| 精产国品一二三产区9977| 一区二区三区四区在线 | 欧洲| 精品国产天线2019| 99视频精品全部免费 在线| 国产麻豆精品精东影业av网站| 国产高清自产拍av在线 | 成人免费无码不卡毛片视频|