在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. OLFM2 Antibody

OLFM2 Antibody

  • 中文名稱：
    OLFM2兔多克隆抗體
  • 貨號：
    CSB-PA016321GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    OLFM2
  • 別名：
    Neuronal olfactomedin related ER localized protein 2 antibody; NOE2 antibody; NOE2_HUMAN antibody; Noelin 2 antibody; Noelin-2 antibody; NOELIN2 antibody; NOELIN2 V1 antibody; Olfactomedin 2 antibody; Olfactomedin-2 antibody; OlfC antibody; Olfm2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human OLFM2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization. Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling.
  • 基因功能參考文獻：
    1. plasma OLFM2 is a potential biomarker for restenosis and may be a novel target for the treatment of restenosis. PMID: 29553861
    2. Our study indicates that OLFM2 is likely to be important in mammalian eye development and disease and should be considered as a gene for human ocular anomalies. PMID: 27844144
    3. Olfm2 physically interacts with serum response factor (SRF) without affecting the SRF-myocardin interaction. PMID: 25298399
    4. The Arg144Gln mutation in OLFM2 is a possible disease-causing mutation in Japanese patients with OAG. Common polymorphisms in OLFM2 and OPTN may interactively contribute to the development of OAG, indicating a polygenic etiology. PMID: 17122126
  • 亞細胞定位：
    Secreted. Cell junction, synapse. Membrane. Nucleus. Cytoplasm.
  • 組織特異性：
    Expressed in aortic smooth muscle (at protein level). In the fetus, expressed in the brain and ocular tissues including lens vesicle and optic cup.
  • 數據庫鏈接：

    HGNC: 17189

    OMIM: 617492

    KEGG: hsa:93145

    STRING: 9606.ENSP00000264833

    UniGene: Hs.169743



主站蜘蛛池模板： 久久精品成人欧美大片| 任我撸在线视频| 一区二区三区中文字幕| 欧美成人h亚洲综合在线观看| 夜夜躁狠狠躁日日躁| 色狠狠久久av五月综合| 国模少妇一区二区三区| 一本一本久久a久久综合精品蜜桃 国产精品人妻久久毛片高清无卡 成视频年人黄网站视频福利 | 巨熟乳波霸若妻在线播放| 国产高清在线精品一区下载| 日本一区二区三区免费播放 | 色噜噜av亚洲色一区二区 | 日本又黄又潮娇喘视频| 99久久国产综合精品1| 欧美日产国产精品| 国产乱国产乱老熟300部视频| 亚洲熟妇久久国内精品| 18禁男女无遮挡啪啪网站| 亚洲自偷精品视频自拍| 欧美亚洲国产成人一区二区三区| 国产欧美va天堂在线电影| 亚洲乱码日产精品bd在观看| 国产乱色精品成人免费视频| 伊人成年网站综合网| 99久久国产露脸精品| 日韩乱码人妻无码中文视频| 国产精品无码久久av| 亚洲精品第一国产综合境外资源| 国产成人亚洲综合色婷婷秒播| 国产成人亚洲综合无码| 国产色在线 | 亚洲| 青青草国产精品欧美成人| 人妻中文乱码在线网站| 国产精品美女被遭强扒开双腿| 两根大肉大捧一进一出好爽视频| 精品国产不卡在线观看免费| 亚洲精品久久久久avwww潮水 | 131mm少妇做爰视频| 韩国理伦片一区二区三区在线播放| 秋霞鲁丝无码一区二区三区| 亚洲成_人网站图片|