在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. OLFM2 Antibody

OLFM2 Antibody

  • 中文名稱：
    OLFM2兔多克隆抗體
  • 貨號：
    CSB-PA016321GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    OLFM2
  • 別名：
    Neuronal olfactomedin related ER localized protein 2 antibody; NOE2 antibody; NOE2_HUMAN antibody; Noelin 2 antibody; Noelin-2 antibody; NOELIN2 antibody; NOELIN2 V1 antibody; Olfactomedin 2 antibody; Olfactomedin-2 antibody; OlfC antibody; Olfm2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human OLFM2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization. Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling.
  • 基因功能參考文獻：
    1. plasma OLFM2 is a potential biomarker for restenosis and may be a novel target for the treatment of restenosis. PMID: 29553861
    2. Our study indicates that OLFM2 is likely to be important in mammalian eye development and disease and should be considered as a gene for human ocular anomalies. PMID: 27844144
    3. Olfm2 physically interacts with serum response factor (SRF) without affecting the SRF-myocardin interaction. PMID: 25298399
    4. The Arg144Gln mutation in OLFM2 is a possible disease-causing mutation in Japanese patients with OAG. Common polymorphisms in OLFM2 and OPTN may interactively contribute to the development of OAG, indicating a polygenic etiology. PMID: 17122126
  • 亞細胞定位：
    Secreted. Cell junction, synapse. Membrane. Nucleus. Cytoplasm.
  • 組織特異性：
    Expressed in aortic smooth muscle (at protein level). In the fetus, expressed in the brain and ocular tissues including lens vesicle and optic cup.
  • 數據庫鏈接：

    HGNC: 17189

    OMIM: 617492

    KEGG: hsa:93145

    STRING: 9606.ENSP00000264833

    UniGene: Hs.169743



主站蜘蛛池模板： 无码视频一区二区三区在线观看 | 9久9久女女热精品视频在线观看| 九九99无码精品视频在线观看| 国产又a又黄又潮娇喘视频| 国产深夜男女无套内射| 少妇无码av无码专区在线观看| 男人扒开女人内裤强吻桶进去| 亚洲制服丝袜av一区二区三区| 亚洲va久久久噜噜噜久久无码| 麻豆精品久久久久久中文字幕无码 | 亚洲毛片多多影院| 中文字幕无码精品亚洲35| 中文人妻无码一区二区三区| 亚洲 欧美 另类 综合 日韩| 亚洲一卡2卡3卡4卡5卡乱码观看| 在线成人精品国产区免费| 丰满少妇女裸体bbw| 黄网站成人片免费视频| 国产免费高清69式视频在线观看 | 日韩中文字幕在线一区二区三区| 在线 偷窥 制服 另类| 日本一卡2卡3卡4卡免费乱码网站| 国产午夜精品一区二区三区不卡| 少妇被黑人到高潮喷出白浆 | 亚洲熟妇无码八v在线播放| 亚洲性夜色噜噜噜网站2258kk| 国产69精品久久久久久久| 2020国产欧洲精品网站| 日本免费人成在线观看网站| 亚洲视频一区| 处破痛哭a√18成年片免费| 清纯唯美经典一区二区| 激情按摩系列片aaaa| 看全色黄大色大片免费久久| 美女被张开双腿日出白浆| 人妻熟妇乱又伦精品视频无广告| 国产精品爽爽久久久久久蜜臀| 天天做天天大爽天天爱| 国产三级视频在线观看视| 在线欧美中文字幕农村电影| 亚洲欧美日韩久久精品|