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  4. OLFM1 Antibody, Biotin conjugated

OLFM1 Antibody, Biotin conjugated

  • 中文名稱：
    OLFM1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA858725LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) OLFM1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    OLFM1
  • 別名：
    AMY antibody; NEUROBLASTOMA PROTEIN antibody; Neuronal olfactomedin-related ER localized protein antibody; Noe1 antibody; NOE1_HUMAN antibody; Noel antibody; Noel1 antibody; Noelin antibody; Noelin1 antibody; OlfA antibody; Olfactomedin 1 antibody; Olfactomedin-1 antibody; Olfm1 antibody; Pancortin 1 antibody; Pancortin antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Noelin protein (374-441AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse. May play an important role in regulating the production of neural crest cells by the neural tube. May be required for normal responses to olfactory stimuli.
  • 基因功能參考文獻：
    1. OLFM1 is a negative regulator of non-canonical NF-kappaB signalling by interacting with and inhibiting NIK. Thus, OLFM1 may serve as a valuable biomarker and therapeutic target for colorectal cancer (CRC) patients. PMID: 27555280
    2. human chorionic gonadotropin stimulated miR-212, which down-regulated OLFM1 and CTBP1 expression in fallopian and endometrial epithelial cells to favor spheroid attachment PMID: 26377223
    3. OLF domains from H. sapiens olfactomedin-1 and M. musculus gliomedin were biophysically, biochemically, and structurally characterized. PMID: 26121352
    4. Down-regulation of OLFM1 in fallopian tube epithelial cells enhances spheroid attachment to fallopian tube. PMID: 25999259
    5. Wnt activation suppresses Olfm-1 expression, and this may predispose a favorable microenvironment of the retained embryo in the Fallopian tube, leading to ectopic pregnancy in humans PMID: 21968811

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  • 亞細胞定位：
    Secreted. Cell junction, synapse. Endoplasmic reticulum. Cell projection, axon. Perikaryon.
  • 數據庫鏈接：

    HGNC: 17187

    OMIM: 605366

    KEGG: hsa:10439

    STRING: 9606.ENSP00000252854

    UniGene: Hs.522484



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