在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

OIP5 Antibody, HRP conjugated

  • 中文名稱:
    OIP5兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA016316LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) OIP5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    OIP5
  • 別名:
    OIP5 antibody; MIS18B antibody; Protein Mis18-beta antibody; Cancer/testis antigen 86 antibody; CT86 antibody; Opa-interacting protein 5 antibody; OIP-5 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein Mis18-beta protein (1-229AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
  • 基因功能參考文獻:
    1. LncRNA OIP5-AS1 suppressed cell viability, promoted radio-induced apoptosis, and enhanced the radiosensitivity of CRC cells by regulating DYRK1A expression through miR-369-3p. PMID: 29773344
    2. LncRNA OIP5-AS1 modulated the expression of Bcl-2 by targeting miR-448 in lung adenocarcinoma cells. PMID: 29247949
    3. interaction network might function as an oncogene in bladder cancer progression PMID: 28843748
    4. The authors demonstrate that CDK1 controls Mis18 complex recruitment to centromeres by regulating oligomerization of M18BP1 through the Mis18alpha:Mis18beta scaffold. PMID: 28059702
    5. High OIP5 expression is associated with bladder cancer. PMID: 28752236
    6. Mitofusin 2 knockdown altered Neisseria gonorrhoeae opacity-associated-interacting protein 5 (OIP5) expression. PMID: 29034772
    7. These findings suggest that OIP5 may be involved in hepatocellular carcinoma (HCC) growth and metastasis and that miR-15b-5p inhibits OIP5-mediated oncogenic signaling in HCC. PMID: 28184024
    8. the Mis18 complex contains dual CENP-C recognition motifs that are combinatorially required to generate robust centromeric localization that leads to CENP-A deposition PMID: 27239045
    9. OIP5 over-expression inhibited hsa-miR-139-5p expression, antagonized its functions and led to the de-repression of its endogenous target NOTCH1, which was a core oncogene in promoting breast cancer progression. PMID: 27916718
    10. Stable binding of Mis18alpha-Mis18beta heterotetramer to centromeres in telophase licenses them for CENP-A deposition. PMID: 26942680
    11. Over-expression of OIP5 was observed in breast tumors. PMID: 26107214
    12. Mis18beta binds with and specifies the centromere localization of HJURP. PMID: 24519934
    13. this study showed betaTrCP-mediated regulation of Mis18beta stability is a mechanism to restrict centromere function of Mis18 complex from late mitosis to early G1 phase. PMID: 24269809
    14. expression of AURKC, OIP5, PIWIL2 and TAF7L differed between patients with Acute myeloid leukemia, myelodysplastic syndrome and healthy controls in a gender-dependent manner PMID: 23292864
    15. OIP5 expression was significantly associated with poor prognosis of lung and esophageal cancer patients PMID: 22129094
    16. These results indicate that knockdown of OIP5 may induce apoptosis in cancer cells. PMID: 20510019
    17. Three human proteins essential for centromere/kinetochore structure and function, hMis18alpha, hMis18beta, and M18BP1, the complex of which is accumulated specifically at the telophase-G1 centromere, are identified.[Mis18alpha, Mis18beta, M18BP1] PMID: 17199038

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
  • 蛋白家族:
    Mis18 family
  • 數據庫鏈接:

    HGNC: 20300

    OMIM: 606020

    KEGG: hsa:11339

    STRING: 9606.ENSP00000220514

    UniGene: Hs.661645



主站蜘蛛池模板: 亚洲熟女综合色一区二区三区| 亚洲精品国产一区黑色丝袜| 精品一二三区久久aaa片| 成人免费国产精品视频 | 午夜免费啪视频在线18| 亚洲 综合 欧美在线视频| 亚洲中文欧美在线视频| 国内免费视频成人精品| 2019一級特黃色毛片免費看 | 人妻少妇无码精品视频区| 无码人妻丰满熟妇啪啪网站| 国产又爽又黄又不遮挡视频| 欧洲熟妇色xxxxx视频| 精品四虎国产在免费观看| 野外少妇激情aa 级视频| 久久久日韩精品一区二区三区| 亚洲精品中文字幕乱码三区| 加勒比一本heyzo高清视频| a国产在线v的不卡视频| 丰满的少妇xxxxx人| 日产精品卡2卡三卡乱码网址| 一本大道东京热无码| 久久国语露脸国产精品电影| 老司机午夜免费精品视频| 中无码人妻丰满熟妇啪啪| 国产欧美日韩精品专区| 国产精品久久久久久久久久妞妞| 无码熟妇人妻av在线影片| 欧美成人精品高清在线播放| 亚洲精品乱码一区二区三区| 成人免费播放视频777777| 图片区 小说区 区 亚洲五月| 粗大猛烈进出高潮视频免费看| 波多野结衣中文字幕久久| 在线偷着国产精选视频| 东京热大乱系列无码| 亚洲 国产 韩国 欧美 在线| 奇米影视888欧美在线观看| 国产一区二区在线影院| 午夜男女爽爽影院免费视频| 综合亚洲综合图区网友自拍|