在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

OGDH Antibody

  • 中文名稱:
    OGDH兔多克隆抗體
  • 貨號:
    CSB-PA016307GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    OGDH
  • 別名:
    2 oxoglutarate dehydrogenase antibody; 2 oxoglutarate dehydrogenase complex component E1 antibody; 2 oxoglutarate dehydrogenase mitochondrial antibody; 2-oxoglutarate dehydrogenase antibody; 2-oxoglutarate dehydrogenase complex component E1 antibody; AKGDH antibody; Alpha ketoglutarate dehydrogenase antibody; Alpha-ketoglutarate dehydrogenase antibody; E1k antibody; mitochondrial antibody; ODO1_HUMAN antibody; OGDC antibody; OGDC E1 antibody; OGDC-E1 antibody; OGDH antibody; Oxoglutarate (alpha ketoglutarate) dehydrogenase (lipoamide) antibody; Oxoglutarate decarboxylase antibody; Oxoglutarate dehydrogenase (lipoamide) antibody; Oxoglutarate dehydrogenase (succinyl transferring) antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human OGDH
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
  • 基因功能參考文獻:
    1. PIK3CA mutant cancer cells require PIK3CA but also require the expression of the TCA cycle enzyme 2-oxoglutarate dehydrogenase (OGDH). PMID: 28396387
    2. oxoglutarate dehydrogenase (OGDH) and lipoic acid synthase (LIAS), which when mutated stabilize HIF1alpha in a non-hydroxylated form. PMID: 27923773
    3. Tissue-specific expression of OGDH splice variants may thus provide a mechanism that tunes the control of the enzyme to the specialized metabolic and signalling needs of individual cell types PMID: 26936970
    4. ATP consumption is demonstrated in respiration-impaired isolated mice and in situ neuronal mitochondria from transgenic mice with dihydrolipoyl succinyltransferase deficiency. PMID: 23475850
    5. Acute inhibition of alpha-ketoglutarate dehydrogenase produces effects on calcium opposite to those in Alzheimer's disease (AD), while the chronic or long-term inhibition of alpha-KGDHC mimicked the AD-related changes in calcium. PMID: 22169199
    6. Differences in oxoglutarate dehydrogenase activity suggest that there is no excess mitochondrial capacity during maximal exercise with a small muscle mass. PMID: 21611730
    7. 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability is regulated by the RING finger ubiquitin ligase Siah PMID: 15466852
    8. Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity. PMID: 15649899
    9. Association with autosomal recessive DOOR syndrome not found. PMID: 17343268

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion matrix. Nucleus.
  • 蛋白家族:
    Alpha-ketoglutarate dehydrogenase family
  • 數據庫鏈接:

    HGNC: 8124

    OMIM: 613022

    KEGG: hsa:4967

    STRING: 9606.ENSP00000222673

    UniGene: Hs.488181



主站蜘蛛池模板: 国产在线看片免费人成视频| 538在线精品视频| 又爽又黄又无遮挡的视频| 国产又黄又爽又色的免费视频 | 亚洲欧美一区二区三区| 久久久精品2019免费观看| 成人无码视频免费播放| 最新av偷拍av偷窥av网站| 日韩一区二区三区精品| 成人h动漫无码网站久久| 男女做爰无遮挡性视频| 小荡货好紧好爽奶头大视频| www插插插无码视频网站| 亚洲一卡2卡三卡四卡精品| 成人啪精品视频网站午夜| 精品综合久久久久久8888| 少妇熟女高潮流白浆| 天天看片视频免费观看| 亚洲综合天堂一区二区三区| 少妇精品久久久一区二区三区| 精品久久久久成人码免费动漫| 亚洲性人人天天夜夜摸| h无码精品3d动漫在线观看| 77777_亚洲午夜久久多人| 女人被狂躁60分钟视频 | 亚洲国产综合无码一区| 日本一区二区三区免费播放视频站| 久久久无码精品亚洲日韩啪啪网站| 少妇人妻邻居| 久久久精品久久日韩一区综合| 亚洲精品综合欧美一区二区三区 | 亚洲.欧美.在线视频| 日本三级吃奶头添泬无码苍井空| 欧美性欧美巨大黑白大战| 精品国产av一区二区果冻传媒| 久久久精品人妻一区二区三区四| 亚洲欧美日韩精品色xxx| av在线 高清不卡区| 久久精品伊人一区二区三区| 狠狠色综合7777久夜色撩人ⅰ| 巨胸喷奶水视频www免费网站|