在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Non-structural polyprotein Antibody

Rare Species
  • 中文名稱:
    Non-structural polyprotein兔多克隆抗體
  • 貨號:
    CSB-PA329710XA01VAZ
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: Non-structural polyprotein antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31.4 kDa
      Observed band size: 36 kDa
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    N/A
  • 別名:
    Non-structural polyprotein (Polyprotein nsP1234) (P1234) [Cleaved into: P123, P123', mRNA-capping enzyme nsP1 (EC 2.1.1.-) (EC 2.7.7.-) (Non-structural protein 1), Protease nsP2 (EC 3.1.3.33) (EC 3.4.22.-) (EC 3.6.1.15) (EC 3.6.4.13) (Non-structural protein 2) (nsP2), Non-structural protein 3 (nsP3), Non-structural protein 3' (nsP3'), RNA-directed RNA polymerase nsP4 (EC 2.7.7.48) (Non-structural protein 4) (nsP4)]
  • 反應種屬:
    Venezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV)
  • 免疫原:
    Recombinant Venezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV) Non-structural polyprotein (27-167aa)
  • 免疫原種屬:
    Venezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Protein G
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Inactive precursor of the viral replicase, which is activated by cleavages carried out by the viral protease nsP2.; The early replication complex formed by the polyprotein P123 and nsP4 synthesizes the minus-strand RNAs (antigenome). Polyprotein P123 is a short-lived polyprotein that accumulates during early stage of infection (Probable). As soon P123 is cleaved into mature proteins, the plus-strand RNAs synthesis begins.; The early replication complex formed by the polyprotein P123' and nsP4 synthesizes minus-strand RNAs (antigenome) (Probable). Polyprotein P123' is a short-lived polyprotein that accumulates during early stage of infection (Probable). As soon P123' is cleaved into mature proteins, the plus-strand RNAs synthesis begins (Probable).; Cytoplasmic capping enzyme that catalyzes two virus-specific reactions: methyltransferase and nsP1 guanylyltransferase. mRNA-capping is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus (Probable). The enzymatic reaction involves a covalent link between 7-methyl-GMP and nsP1, whereas eukaryotic capping enzymes form a covalent complex only with GMP. NsP1 capping consists in the following reactions: GTP is first methylated into 7-methyl-GMP and then is covalently linked to nsP1 to form the m7GMp-nsP1 complex from which 7-methyl-GMP complex is transferred to the mRNA to create the cap structure. NsP1 is also needed for the initiation of the minus-strand RNAs synthesis. Probably serves as a membrane anchor for the replication complex composed of nsP1-nsP4. Nsp1 is needed for the initiation of the minus-strand RNAs synthesis. Palmitoylated nsP1 is remodeling host cell cytoskeleton, and induces filopodium-like structure formation at the surface of the host cell.; Multifunctional protein whose N-terminus is part of the RNA polymerase complex and displays NTPase, RNA triphosphatase and helicase activities. NTPase and RNA triphosphatase are involved in viral RNA capping and helicase keeps a check on the dsRNA replication intermediates. The C-terminus harbors a protease that specifically cleaves the polyproteins and releases the mature proteins. Required for the shutoff of minus-strand RNAs synthesis. Inhibits host translation to ensure maximal viral gene expression and evade host immune response.; Seems to be essential for minus-strand RNAs and subgenomic 26S mRNAs synthesis. Displays mono-ADP-ribosylhydrolase activity. ADP-ribosylation is a post-translational modification that controls various processes of the host cell and the virus probably needs to revert it for optimal viral replication. Binds proteins of FXR family and sequesters them into the viral RNA replication complexes thereby inhibiting the formation of host stress granules on viral mRNAs. The nsp3-FXR complexes bind viral RNAs and probably orchestrate the assembly of viral replication complexes, thanks to the ability of FXR family members to self-assemble and bind DNA.; Seems to be essential for minus-strand RNAs and subgenomic 26S mRNAs synthesis. Displays mono-ADP-ribosylhydrolase activity (Probable). ADP-ribosylation is a post-translational modification that controls various processes of the host cell and the virus probably needs to revert it for optimal viral replication (Probable). Binds proteins of FXR family and sequesters them into the viral RNA replication complexes thereby inhibiting the formation of host stress granules on viral mRNAs (Probable). The nsp3'-FXR complexes bind viral RNAs and probably orchestrate the assembly of viral replication complexes, thanks to the ability of FXR family members to self-assemble and bind DNA (Probable).; RNA dependent RNA polymerase. Replicates genomic and antigenomic RNA by recognizing replications specific signals. The early replication complex formed by the polyproteins P123/P123' and nsP4 synthesizes minus-strand RNAs. The late replication complex composed of fully processed nsP1-nsP4 is responsible for the production of genomic and subgenomic plus-strand RNAs.
  • 亞細胞定位:
    [Polyprotein P1234]: Host cytoplasmic vesicle membrane; Peripheral membrane protein.; [Polyprotein P123']: Host cytoplasmic vesicle membrane; Peripheral membrane protein.; [Polyprotein P123]: Host cytoplasmic vesicle membrane; Peripheral membrane protein.; [mRNA-capping enzyme nsP1]: Host cytoplasmic vesicle membrane; Lipid-anchor. Host cell membrane; Lipid-anchor; Cytoplasmic side. Host cell projection, host filopodium.; [Protease nsP2]: Host cytoplasmic vesicle membrane; Peripheral membrane protein. Host nucleus. Host cytoplasm.; [Non-structural protein 3]: Host cytoplasmic vesicle membrane; Peripheral membrane protein.; [Non-structural protein 3']: Host cytoplasmic vesicle membrane; Peripheral membrane protein.; [RNA-directed RNA polymerase nsP4]: Host cytoplasmic vesicle membrane; Peripheral membrane protein.


主站蜘蛛池模板: 亚洲中文有码字幕日本第一页| 亚洲成av人综合在线观看| 久久aⅴ无码av高潮av喷吹| 日韩精品真人荷官无码| 成人做受120秒试看试看视频| 日本阿v网站在线观看中文| 熟女少妇人妻中文字幕| 西西人体www大胆高清| 久久96国产精品久久久| 日韩人妻无码精品系列专区 | 国产成人无码a区在线| 国语自产视频在线| 人妻巨大乳hd免费看| 2018国产精华国产精品| 又黄又硬又湿又刺激视频免费| 人妻三级日本三级日本三级极| 一本一道波多野结衣av中文| 亚洲精品久久久久久无码色欲四季| 久久精品aⅴ无码中文字字幕不卡| 欧美日韩国产中文高清视频| 国产日产久久高清欧美一区 | 人妻人人看人妻人人添| 国产三级做爰在线播放| 国产亚洲精品久久久久久无几年桃| 伊人色综合久久天天小片| 无码国产玉足脚交极品网站| 久久婷婷五月综合色奶水99啪| 久久久久久久人妻无码中文字幕爆| 风流少妇按摩来高潮| 色欲av久久综合人妻无码| 夫妻免费无码v看片| 欧美性插b在线视频网站| 99热国产这里只有精品9| 成人网站www污污污网站| 久久99精品久久久大学生| 人人鲁人人莫人人爱精品| 欧洲无线码免费一区| 亚洲精品成人网站在线观看| 香蕉影院在线观看| 婷婷色香合缴缴情av第三区| 国产男女嘿咻视频在线观看|