在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NYX Antibody

  • 中文名稱:
    NYX兔多克隆抗體
  • 貨號:
    CSB-PA016237ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: NYX antibody at 4.91 μg/ml
      + Mouse liver tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 52 kDa
      Observed band size: 52, 32, 39 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA016237ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) NYX Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    NYX
  • 別名:
    CLRP antibody; CSNB1 antibody; CSNB4 antibody; leucine-rich repeat protein antibody; Nyctalopin antibody; NYX antibody; NYX_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Nyctalopin protein (282-481AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Two Novel NYX Gene Mutations in the Chinese Families with X-linked Congenital Stationary Night Blindness were described. PMID: 26234941
    2. Four potential pathogenic variations in the NYX gene were found in four families with high myopia with or without CSNB1. PMID: 25802485
    3. Loss of ERG amplitude and apparent ON-pathway dysfunction at high temporal frequencies distinguish this patient with a Trp237Ter NYX mutation from those with other previously reported NYX mutations. PMID: 23289809
    4. A missense mutation (c.529_530GC>AT or p.Ala177Met) was identified in one male subject with high myopia, but not in 200 male emmetropes. PMID: 23406521
    5. A mutation was identified in NYX in 20 male patients with Congenital Stationary Night Blindness 1. PMID: 23714322
    6. The results expand the mutation spectrum of NYX, CACNA1F and GRM6. They also suggest that NYX mutations are a common cause of congenital stationary night blindness (CSNB). PMID: 22735794
    7. A proteomic search for proteins associated with nyctalopin in the retina identified TRPM1 as the binding partner and nyctalopin additionally interacts with mGluR6 receptor. PMID: 21832182
    8. Phenotypic expression of the complete type of X-linked congenital stationary night blindness in patients with different mutations in the NYX gene. PMID: 12397430
    9. Seven in-frame deletion, splicing, missense, nonsense, and frameshift mutations were identified segregating with X-linked congenital stationary night blindness in the NYX gene. PMID: 12552565
    10. Human and mouse nyctalopin are membrane-bound extracellular proteins and are functionally conserved. PMID: 14507859
    11. The results implicated a specific on-pathway signaling deficiency in CSNB1-NYX males with no evidence of off-pathway involvement. Likewise, rapid-on/off ramping stimuli also indicated that the functional deficit was localized to the on pathway. PMID: 15331616
    12. In a pool of eight diagnosed XLCSNB (X-linked congenital stationary night blindness) patients, five showed a sequence variation in the CACNA1F and two in the NYX gene. PMID: 15761389
    13. Results support a role for nyctalopin in synaptic transmission and/or synapse formation at ribbon synapses in the retina. PMID: 16553780
    14. X-linked congenital night blindness mutations are reported in Chinese males in two families. PMID: 16670814
    15. Mutations in NYX may cause high myopia without congenital stationary night blindness. PMID: 17392683
    16. The c.855delG deletion in NYX seems to be a common mutation associated with CSNB in the Flemish population from Belgium. PMID: 18617546
    17. The nob (no b-wave) mouse model of CSNB1 (complete form of human X-linked congenital stationary night blindness) involves an 85-bp deletion in the nyx gene. PMID: 12506099
    18. Novel mutations of NYX were identified in two Chinese families with CSNB1 and myopia. PMID: 16670814

    顯示更多

    收起更多

  • 相關疾病:
    Night blindness, congenital stationary, 1A (CSNB1A)
  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Small leucine-rich proteoglycan (SLRP) family, SLRP class IV subfamily
  • 組織特異性:
    Expressed in kidney and retina. Also at low levels in brain, testis and muscle. Within the retina, expressed in the inner segment of photoreceptors, outer and inner nuclear layers and the ganglion cell layer.
  • 數據庫鏈接:

    HGNC: 8082

    OMIM: 300278

    KEGG: hsa:60506

    STRING: 9606.ENSP00000340328

    UniGene: Hs.302019



主站蜘蛛池模板: 男女真人国产牲交a做片野外| 中文字幕人乱码中文字幕| 一二三四免费观看在线视频中文版 | 亚洲国产精品无码中文字| 亚洲日韩一区二区| 日韩人妻无码一区二区三区| 久久精品国产99国产精偷 | 狠狠色狠狠色狠狠五月| 日本黄网站免费| 国产成人无码a区在线观看导航| 国产精品亚洲一区二区三区喷水| 99久热re在线精品视频| 麻豆果冻传媒2021精品传媒一区下载 | 人妻中出无码一区二区三区| 亚洲愉拍自拍另类天堂| 明星性猛交ⅹxxx乱大交| 风流少妇按摩来高潮| 动漫av纯肉无码av电影网| 人妻在线无码一区二区三区 | 国产真实伦在线观看| 国产精品久久久久久一区二区三区| 成年片色大黄全免费软件到 | 国产精品高清一区二区不卡片| 色噜噜噜亚洲男人的天堂| 久久不见久久见免费影院3| 鲁一鲁一鲁一鲁一澡| 久久亚洲精品中文字幕一区| 奇米影视7777狠狠狠狠影视| 国产精品成人无码免费| 熟妇人妻无码中文字幕老熟妇| 国产无遮挡色视频免费观看性色| 欧美综合在线激情专区| 鲁丝一区二区三区免费| 国产高清午夜人成在线观看| 亚洲成成品网站源码中国有限公司| 国产精品久久久久久亚洲毛片| 中文字幕欧美人妻精品一区| 婷婷五月综合丁香在线| 精品国产成人高清在线观看| 乱妇乱女熟妇熟女网站| 精品国产一区二区三区四区精华液|