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NXPH1 Antibody

  • 中文名稱：
    NXPH1兔多克隆抗體
  • 貨號：
    CSB-PA016227LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA016227LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NXPH1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NXPH1
  • 別名：
    Nbla00697 antibody; Neurexophilin 1 antibody; Neurexophilin-1 antibody; Neurexophilin1 antibody; NPH1 antibody; NXPH 1 antibody; NXPH1 antibody; NXPH1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Neurexophilin-1 protein (22-271AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，NXPH1 Antibody (CSB-PA016227LA01HU)，的標記方式是Non-conjugated。對于NXPH1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA016227LB01HU NXPH1 Antibody, HRP conjugated ELISA
    FITC CSB-PA016227LC01HU NXPH1 Antibody, FITC conjugated
    Biotin CSB-PA016227LD01HU NXPH1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
  • 基因功能參考文獻：
    1. identification of SNPs within the IQCJ, NXPH1, PHF17 and MYB genes partly explaining the large interindividual variability observed in plasma triglyceride levels in response to an n-3 fatty acid supplementation PMID: 27160456
    2. A genome-wide association study (GWAS) identified loci associated with the plasma triglyceride (TG) response to omega-3 fatty acid (FA) supplementation in IQCJ, NXPH1, PHF17 and MYB. PMID: 28134766
    3. The role of NXPH1 in in paranoid schizophrenia development in Russians. PMID: 26410934
    4. Rs2349775 (NXPH1) and rs17837965 (CDC42) were associated with diarrhoea and constipation predominant irritable bowel syndrome, respectively, in two independent cohorts. PMID: 24041540
    5. Data indicate that median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis. PMID: 22930747
    6. Data indicate taht candidate genes ACTB, BZW, OCM, MACC1, NXPH1, PRPS1L1, RAC1 and RPA3, which lie within the DFNB90 region, were sequenced and no potentially causal variants were identified. PMID: 21734401
    7. results demonstrate the presence and function of a regulated signaling axis in hematopoiesis centered on NRXN1alpha and its modulation by DAG1 and NXPH1 PMID: 21628410
    8. In rat, neurexophilin 1 forms a very tight complex with neurexin I alpha. PMID: 8699246
    9. In rat, the secreted ligand for alpha-neurexin, neurexophilin 1, is expressed in the postnatal olfactory bulb. PMID: 12141453

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Neurexophilin family
  • 數據庫鏈接：

    HGNC: 20693

    OMIM: 604639

    KEGG: hsa:30010

    STRING: 9606.ENSP00000384551

    UniGene: Hs.487564



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