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  4. NXF5 Antibody, FITC conjugated

NXF5 Antibody, FITC conjugated

  • 中文名稱：
    NXF5兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA016223LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) NXF5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NXF5
  • 別名：
    NXF5 antibody; TAPL1 antibody; Nuclear RNA export factor 5 antibody; TAP-like protein 1 antibody; TAPL-1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Nuclear RNA export factor 5 protein (1-200AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons.
  • 基因功能參考文獻(xiàn)：
    1. study of an Australian pedigree in which focal segmental glomerulosclerosis co-segregates with progressive heart block; study found 2 mutations NXF5-R113W and ALG13-T141L segregated with disease phenotype; predicted the NXF5 R113W mutation to be deleterious; cellular studies support a role in the stability and localization of the protein suggesting a causative role PMID: 23686279
    2. Mutations of the NXF5 gene is associated with X-linked mental retardation PMID: 12784308
  • 相關(guān)疾病：
    A chromosomal aberration involving NXF5 has been observed in one patient with a syndromic form of mental retardation and short stature. Pericentric inversion inv(X)(p21.1;q22) that interrupts NXF5.
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Note=Mainly localized in the cytoplasm of cells and more particularly in the cell body and neurites of hippocampal neurons. Although nuclear localization is also observed. Not detected at nuclear rim.
  • 蛋白家族：
    NXF family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8075

    OMIM: 300319

    KEGG: hsa:55998

    STRING: 9606.ENSP00000426978

    UniGene: Hs.307077



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