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NUP88 Antibody

  • 中文名稱:
    NUP88兔多克隆抗體
  • 貨號:
    CSB-PA004698
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of K562 cells using Nup88 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    88 kDa nucleoporin antibody; karyoporin antibody; Nuclear pore complex protein 88 antibody; Nuclear pore complex protein Nup88 antibody; Nuclear pore complex protein88 antibody; Nucleoporin 88 antibody; Nucleoporin 88 kDa antibody; Nucleoporin 88kDa antibody; Nucleoporin Nup88 antibody; Nucleoporin88 antibody; Nucleoporin88kDa antibody; Nup 84 antibody; NUP 88 antibody; Nup84 antibody; NUP88 antibody; NUP88_HUMAN antibody; Prei 2 antibody; Prei2 antibody; Preimplantation protein 2 antibody; Preimplantation protein2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Nup88.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of nuclear pore complex.
  • 基因功能參考文獻:
    1. Overexpression of the NUP88 is associated with cancer. PMID: 27636375
    2. Nup88 may be related to the occurrence of endometrial cancers and premalignant lesions PMID: 26839161
    3. These findings demonstrate that the NUP88-NUP98-RAE1-APC/CCDH1 axis contributes to aneuploidy PMID: 26731471
    4. Nup62 and Nup88 protein levels were significantly decreased upon knockdown of O-GlcNAc transferase. PMID: 23777819
    5. Serum Nup88 might be a candidate for a new biomarker implicated in the development and aggressiveness of colorectal cancer PMID: 21863385
    6. Nup88 mRNA was overexpressed in colorectal cancers and the overexpression was associated with cancer development and aggressiveness. PMID: 21896994
    7. Data suggest that a pool of Nup88 on the nuclear side of the nuclear pore complex provides a novel, unexpected binding site for nuclear lamin A. PMID: 21289091
    8. association found between myometrial invasion and Nup88 expression in endometrial carcinoma PMID: 20973273
    9. Gambogic acid exerts its anti-leukemia effects by regulating the expression and distribution of nucleoporin Nup88. PMID: 17828493
    10. proper expression of Nup88 is critical for preventing aneuploidy formation and tumorigenesis. PMID: 20497554
    11. High Nup88 mRNA expression levels correlated with ductal and tubular histology, nuclear grade 3, absence of hormone receptors, expression of c-erb-B2 oncogene and mutant p53 protein, high proliferation, DNA aneuploidy, and axillary node invasion. PMID: 14999780
    12. A monoclonal antibody for Nup88 in an experimental model for studying the role played by Nup88 during cell development and differentiation. PMID: 15300515
    13. the Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export PMID: 16675447
    14. Our data strongly indicate a dichotomous role for Nup88 in non-neoplastic and neoplastic conditions of the liver. PMID: 17007055
    15. The antitumor activity of deguelin was related to up-regulating the expression of Nup98 and down-regulating Nup88 protein. PMID: 17650673
    16. The formation of high molecular mass complexes containing importin-alpha, Nup153 and Nup88 is increased upon oxidant treatment. PMID: 18068677
    17. Nup88 is up-regulated in response to hypertonic stress and acts to retain TonEBP in the nucleus, activating transcription of critical osmoprotective genes. PMID: 18606815
    18. Nup88 is significantly overexpressed in high-grade CIN lesions and ISCC compared with normal ectocervical squamous epithelia and CIN1. PMID: 19751906

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  • 亞細胞定位:
    Nucleus, nuclear pore complex.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 8067

    OMIM: 602552

    KEGG: hsa:4927

    STRING: 9606.ENSP00000458954

    UniGene: Hs.584784



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