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NUP50 Antibody

  • 中文名稱:
    NUP50兔多克隆抗體
  • 貨號:
    CSB-PA018458
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA018458(NUP50 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, 293T cells, A549 cells, HT29 cells, Primary antibody: CSB-PA018458(NUP50 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    NUP50
  • 別名:
    50 kDa nucleoporin antibody; NPAP60 antibody; NPAP60L antibody; Nuclear pore associated protein 60L antibody; Nuclear pore complex protein Nup50 antibody; Nuclear pore-associated protein 60 kDa-like antibody; Nucleoporin 50 antibody; Nucleoporin 50kDa antibody; Nucleoporin Nup50 antibody; Nup50 antibody; NUP50_HUMAN antibody; PRO1146 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Fusion protein of Human NUP50
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
  • 基因功能參考文獻:
    1. Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha5. PMID: 22130666
    2. Results suggest that Npap60L and Npap60S function differently in nuclear protein import. PMID: 20016008
  • 亞細胞定位:
    Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
  • 組織特異性:
    Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.
  • 數據庫鏈接:

    HGNC: 8065

    OMIM: 604646

    KEGG: hsa:10762

    STRING: 9606.ENSP00000345895

    UniGene: Hs.475103



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