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  4. NUP43 Antibody, Biotin conjugated

NUP43 Antibody, Biotin conjugated

  • 中文名稱：
    NUP43兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA844045LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NUP43 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NUP43
  • 別名：
    NUP43Nucleoporin Nup43 antibody; Nup107-160 subcomplex subunit Nup43 antibody; p42 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Nucleoporin Nup43 protein (1-200AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
  • 基因功能參考文獻：
    1. High NUP43 expression was an independent prognostic factor of poor overall survival in luminal A subtype and in HER2+ subtype breast cancer. PMID: 29402145
    2. Data present the crystal structure of full length Nup43 and show that it adopts a canonical WD40 fold similar to other members of the family and interacts with Nup85-Seh1L complex to form a ternary complex. PMID: 26391640
  • 亞細胞定位：
    Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
  • 數據庫鏈接：

    HGNC: 21182

    OMIM: 608141

    KEGG: hsa:348995

    STRING: 9606.ENSP00000342262

    UniGene: Hs.510375



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