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  4. NSUN5 Antibody, Biotin conjugated

NSUN5 Antibody, Biotin conjugated

  • 中文名稱：
    NSUN5兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA839386LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NSUN5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NSUN5
  • 別名：
    FLJ10267 antibody; MGC986 antibody; NOL1 antibody; NOL1-related protein antibody; NOL1/NOP2/Sun domain family member 5 antibody; NOL1R antibody; NOP2/Sun domain family, member 5 antibody; NOP2/Sun domain family, member 5A antibody; NSUN5 antibody; NSUN5_HUMAN antibody; p120 antibody; Putative methyltransferase NSUN5 antibody; WBSCR20 antibody; WBSCR20A antibody; Williams Beuren syndrome chromosome region 20A antibody; Williams-Beuren syndrome chromosomal region 20A protein antibody; Williams-Beuren syndrome critical region protein 20 copy A antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Probable 28S rRNA (cytosine-C(5))-methyltransferase protein (362-466AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development.
  • 基因功能參考文獻：
    1. Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome PMID: 11978965
  • 相關疾病：
    NSUN5 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
  • 亞細胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
  • 組織特異性：
    Ubiquitous. Detected in placenta, heart and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 16385

    OMIM: 615732

    KEGG: hsa:55695

    STRING: 9606.ENSP00000309126

    UniGene: Hs.510927



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