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  4. NSUN4 Antibody, Biotin conjugated

NSUN4 Antibody, Biotin conjugated

  • 中文名稱：
    NSUN4兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA850270LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NSUN4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NSUN4
  • 別名：
    5 methylcytosine rRNA methyltransferase NSUN4 antibody; EC=2.1.1.- antibody; NOL1/NOP2/Sun domain family member 4 antibody; NOL1/NOP2/Sun domain family, member 4 antibody; NOP2/Sun domain family, member 4 antibody; Nsun4 antibody; NSUN4_HUMAN antibody; Putative methyltransferase NSUN4 antibody; RP4-603I14.2 antibody; Shtap antibody; Sperm head and tail associated protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human 5-methylcytosine rRNA methyltransferase NSUN4 protein (26-284AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.
  • 基因功能參考文獻：
    1. It involves in epigenetic changes during the progression of Alzheimer disease pathology. PMID: 24387984
    2. analysis of the 3D crystal structure of the human MTERF4-NSUN4 complex PMID: 22949673
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19086053
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
  • 數據庫鏈接：

    HGNC: 31802

    OMIM: 615394

    KEGG: hsa:387338

    STRING: 9606.ENSP00000419740

    UniGene: Hs.163424



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