在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NRCAM Antibody

NRCAM Antibody

  • 中文名稱：
    NRCAM兔多克隆抗體
  • 貨號：
    CSB-PA016074LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA016074LA01HU diluted at 1:200 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA016074LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of 293 cells with CSB-PA016074LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NRCAM Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NRCAM
  • 別名：
    Bravo antibody; hBravo antibody; Neuronal cell adhesion molecule antibody; Neuronal surface protein Bravo antibody; Ng CAM related antibody; Ng-CAM-related antibody; NgCAM related cell adhesion molecule antibody; NgCAM-related cell adhesion molecule antibody; Nr CAM antibody; Nr-CAM antibody; Nrcam antibody; NRCAM_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Neuronal cell adhesion molecule protein (1194-1299AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，NRCAM Antibody (CSB-PA016074LA01HU)，的標記方式是Non-conjugated。對于NRCAM Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA016074LB01HU NRCAM Antibody, HRP conjugated ELISA
    FITC CSB-PA016074LC01HU NRCAM Antibody, FITC conjugated
    Biotin CSB-PA016074LD01HU NRCAM Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
  • 基因功能參考文獻：
    1. Increased gene expression of NrCAM may be used as a potential diagnostic marker for papillary thyroid cancer. PMID: 27732334
    2. A high level of Nr-CAM expression is associated with favorable tumor phenotype and reduced risk of prostate cancer recurrence. PMID: 23338556
    3. Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM PMID: 21876539
    4. mechanisms of NrCAM participation in development and how these might be perturbed in disorders are reviewed. [review] PMID: 22182708
    5. Nr-CAM protein expression is upregulated in colorectal cancer tissues; Nr-CAM overexpression is an independent marker of poor prognosis among advanced CRC patients, and a possible predictive marker for non-beneficence to 5-fluorouracil-based chemotherapy PMID: 21718388
    6. Identification of endothelial cell genes expressed in an in vitro model of angiogenesis: induction of ESM-1, (beta)ig-h3, and NrCAM PMID: 11866539
    7. induction of Nr-CAM transcription plays a role in melanoma and colon cancer tumorigenesis PMID: 12183361
    8. NrCAM is overexpressed in human papillary thyroid carcinoma at the mRNA and protein levels, whatever the tumour stage. PMID: 17667921
    9. Distinct cytokeratin 7, cytokeratin 19, & neuronal cell adhesion molecule staining patterns are seen in hepatic adenoma & focal nodular hyperplasia possibly suggest activation of different subsets of hepatic progenitor/stem cell. PMID: 18602664
    10. our results indicated that the NRCAM gene is one of the strong candidate genes for autism PMID: 18664314

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Secreted.
  • 蛋白家族：
    Immunoglobulin superfamily, L1/neurofascin/NgCAM family
  • 組織特異性：
    Detected in all the examined tissues. In the brain it was detected in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
  • 數據庫鏈接：

    HGNC: 7994

    OMIM: 601581

    KEGG: hsa:4897

    STRING: 9606.ENSP00000368314

    UniGene: Hs.21422



主站蜘蛛池模板： 国产乱人伦av在线无码| 国产精品你懂的在线播放| 丰满的人妻hd高清日本| 亚洲 丝袜 制服 欧美 另类| 亚洲中文字幕丝祙制服| 亚洲中文字幕av每天更新| 国产精品va在线观看丝瓜影院| 国产熟女高潮视频| 精品久久久无码人妻中文字幕| 欧美叉叉叉bbb网站| 日韩精品一区二区三区vr| 午夜无码片在线观看影院y| 天天天天躁天天爱天天碰| 国产精品激情| 成人性生交片无码免费看| 久久久亚洲精品无码| 欧美精品黑人粗大| 日韩人妻无码免费视频一区二区| 欧美人与性动交ccoo| 开心五月色婷婷综合开心网| 特殊重囗味sm在线观看无码| 国产乱子伦一区二区三区四区五区| 亚洲色无码中文字幕手机在线| 欧美成人一区二区三区在线观看 | 国产在线精品视频免费观看| 天堂一区人妻无码| 成人av在线一区二区三区| 国产区在线观看成人精品| 202丰满熟女妇大| 日韩va中文字幕无码电影| 国产亚洲视频在线观看播放| 国产成人亚洲精品无码车a | 无码人妻久久1区2区3区| av天堂亚洲区无码先锋影音| 色综合久久蜜芽国产精品| 2012中文字幕在线视频| 亚洲男人综合久久综合天堂| 真人与拘做受免费视频一| 亚洲精品一区二区久| 色欲av巨乳无码一区二区| 日本一道高清一区二区三区|