在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NRBP1 Antibody

  • 中文名稱:
    NRBP1兔多克隆抗體
  • 貨號:
    CSB-PA883410ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA883410ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) NRBP1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    NRBP1
  • 別名:
    BCON3 antibody; MADM antibody; MUDPNP antibody; Multiple domain putative nuclear protein antibody; Myeloid leukemia factor 1 adaptor molecule antibody; NRBP antibody; NRBP_HUMAN antibody; NRBP1 antibody; Nuclear receptor binding protein antibody; Nuclear receptor-binding protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Nuclear receptor-binding protein (406-535AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
  • 基因功能參考文獻:
    1. Study have identified a gout risk gene, NRBP1,and demonstrated that increased NRBP1 expression in gout patients may be regulated through methylation-dependent binding of TFAP2A to the B1 region, a 72 bp upstream of NRBP1 transcription start site. PMID: 28932319
    2. The present study deals with the molecular modeling of the viral protein (NS3 of DENV1-4), the host protein (NRBP) and their interactions through protein-protein docking study. PMID: 24910013
    3. Targeting this we performed homology modeling and protein-protein docking study of NS3 with NRBP (Nuclear Receptor Binding Protein) of human as it has been proved that NS3 of DENV interacts with NRBP which causes cellular trafficking in human cell. PMID: 24372240
    4. High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth. PMID: 22473923
    5. It was shown that NRBP1 is a tumour suppressor that plays a critical role in intestinal cell homoeostasis. NRBP1 levels are reduced in a wide variety of human tumours. Reduced NRBP1 levels in lung cancer correlates with a poor prognosis. PMID: 22510880
    6. Interaction of the small GTPase Rac3 with NRBP: results suggest that NRBP functions in subcellular trafficking and may be directed to specific subcellular locations through interaction with small GTPases of the Rho family PMID: 11956649
    7. mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1 PMID: 12176995
    8. NS3 protein of dengue virus type 2 interacted specifically with nuclear receptor binding protein, a host cellular protein that influences trafficking between the endoplasmic reticulum and Golgi, and that interacts with Rac3 PMID: 15084397

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性:
    Ubiquitously expressed in all tissues examined with high levels in the testis.
  • 數據庫鏈接:

    HGNC: 7993

    OMIM: 606010

    KEGG: hsa:29959

    STRING: 9606.ENSP00000233557

    UniGene: Hs.515876



主站蜘蛛池模板: 天天躁日日躁狠狠躁视频2021| 亚洲精品成人网线在线播放va| 国内偷窥一区二区三区视频| 无码精品黑人一区二区三区| 极品少妇被啪到呻吟喷水| 精品人妻av区波多野结衣 | 国产超级va在线观看视频| 少妇高潮喷水久久久久久久久久| 极品尤物被啪到呻吟喷水| 青草精品国产福利在线视频| 国产一区视频一区欧美| 精品欧美一区二区三区久久久| 苍井空亚洲精品aa片在线播放| 黄网站成人片免费视频| 无遮挡免费高清羞羞视频| 黑人巨茎大战白人美女| 国产偷国产偷亚洲清高| 久久久久久国产精品mv| 国产乱辈通伦影片在线播放亚洲| 久久久久成人精品免费播放动漫 | 免费裸体黄网站18禁免费| 欧美国产日韩a欧美在线观看| 久久午夜伦鲁片免费无码| 日本中国内射bbxx| 精品婷婷色一区二区三区| 日日碰狠狠添天天爽五月婷| 亚洲欧洲精品成人久久曰| 人妻无码一区二区三区av| 性av盈盈无码天堂| 亚洲日本在线电影| 色偷偷av男人的天堂| 中国肥老太婆高清video| 免费一区二区无码东京热| 国产精品久久久影视青草| 日韩精品一卡2卡三卡4卡| 国产乱子伦一区二区三区视频播放| 天天狠天天透天干天天怕∴| 成人午夜又粗又硬又长| a毛片免费全部播放自慰| 国产日韩av在线播放| 色欲av无码一区二区人妻|