在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NR2C1 Antibody

NR2C1 Antibody

  • 中文名稱：
    NR2C1兔多克隆抗體
  • 貨號：
    CSB-PA016051ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA016051ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA016051ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NR2C1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NR2C1
  • 別名：
    NR2C1 antibody; TR2 antibody; Nuclear receptor subfamily 2 group C member 1 antibody; Orphan nuclear receptor TR2 antibody; Testicular receptor 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
  • 基因功能參考文獻：
    1. DRED is a 540 kDa complex containing the nuclear orphan receptors TR2 and TR4, which form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites. TR2 & 4 mRNAs are expressed at all stages of murine and human erythropoiesis. PMID: 12093744
    2. TR2 that may exert an important repressor in regulating ER activity in mammary glands. PMID: 12093804
    3. TR2 and TR4 can have distinct functions. Existence of differential and bi-directional regulation between PPAR alpha and TR2/TR4. Possible roles in PPAR alpha signaling pathway in human keratinocytes. PMID: 12615366
    4. TR2 may function as a negative modulator to suppress androgen receptor function in prostate cancer. Further studies on how to control TR2 function may result in the ability to modulate AR function in prostate cancer. PMID: 12949936
    5. The NF1-A transcription factor plays an important role in the transcriptional activation of the TR2 gene expression via a promoter activating cis-element. PMID: 17010934

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus, PML body.
  • 蛋白家族：
    Nuclear hormone receptor family, NR2 subfamily
  • 數據庫鏈接：

    HGNC: 7971

    OMIM: 601529

    KEGG: hsa:7181

    STRING: 9606.ENSP00000333275

    UniGene: Hs.108301



主站蜘蛛池模板： 日本老妇人乱xxy| 凹凸在线无码免费视频| 色噜噜狠狠一区二区三区| 国产亚洲日韩在线播放更多| 欧美性群另类交| 朝鲜女子内射杂交bbw| 亚洲另类春色校园小说| 天天干天天射天天操| 国产成人综合久久精品推下载| 精品日产一卡二卡| 精品av综合导航| 欧美又大粗又爽又黄大片视频| 午夜福利麻豆国产精品| 骚虎成人免费99xx| 亚洲 a v无 码免 费 成 人 a v| 亚洲精品无码久久久久| 一边啪啪的一边呻吟声口述| 亚洲欲色欲色xxxxx在线| 欧美亚洲综合在线一区| 国产成人麻豆精品午夜福利在线| 亚洲男人综合久久综合天堂| 亚洲人成网站在小说| 无码中文字幕在线播放2| 性强烈的欧美三级视频| 色五月丁香五月综合五月| 奇米影视7777久久精品| 久久99精品国产99久久6尤物 | 午夜寂寞少妇aaa片毛片| 97人洗澡人人澡人人爽人人模| 天堂va视频一区二区| 国产成人精品一区二区三区免费| 无码一区二区三区中文字幕| 国产精品免费观看调教网| 337p日本欧洲亚洲大胆精品| 色综合久久中文综合网| 韩国无码av片在线观看| 久久天天躁狠狠躁夜夜2019| 国产乱xxxxx97国语对白| 午夜a理论片在线播放| 国产牛仔裤网站精品| 精品乱码一区内射人妻无码|