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NPL Antibody

  • 中文名稱：
    NPL兔多克隆抗體
  • 貨號(hào)：
    CSB-PA874830LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse brain tissue
      All lanes: NPL antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 36, 34, 32, 27, 13 kDa
      Observed band size: 36 kDa
    • Immunofluorescent analysis of Hela cells using CSB-PA874830LA01HU at dilution of 1: 100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) NPL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NPL
  • 別名：
    0610033B02Rik antibody; C112 antibody; C1orf13 antibody; Dihydrodipicolinate synthase antibody; Dihydrodipicolinate synthetase homolog 1 antibody; MGC149582 antibody; MGC61869 antibody; N-acetylneuraminate lyase antibody; N-acetylneuraminate pyruvate-lyase antibody; N-acetylneuraminic acid aldolase antibody; NAL antibody; NALase antibody; NPL antibody; NPL_HUMAN antibody; NPL1 antibody; RP11-249O6.1 antibody; Sialate lyase antibody; Sialate-pyruvate lyase antibody; Sialic acid aldolase antibody; Sialic acid lyase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human N-acetylneuraminate lyase protein (17-77AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，NPL Antibody (CSB-PA874830LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于NPL Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA874830LB01HU NPL Antibody, HRP conjugated ELISA
    FITC CSB-PA874830LC01HU NPL Antibody, FITC conjugated
    Biotin CSB-PA874830LD01HU NPL Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Experiments show the true substrate is aceneuramate (linearized Neu5Ac).
  • 基因功能參考文獻(xiàn)：
    1. an NPL splice variant is mainly expressed in human liver, kidney and peripheral blood leukocytes PMID: 16147865
    2. 3D structure model of N-acetylneuraminate lyase from human (hNAL, EC 4.1.3.3) was created and refined PMID: 19057931
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    DapA family, NanA subfamily
  • 組織特異性：
    Isoform 2 is expressed in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocyte.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 16781

    OMIM: 611412

    KEGG: hsa:80896

    STRING: 9606.ENSP00000258317

    UniGene: Hs.496969



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