在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NPAS4 Antibody

  • 中文名稱:
    NPAS4兔多克隆抗體
  • 貨號:
    CSB-PA814204LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: SH-SY5Y whole cell lysate
      All lanes: NPAS4 antibody at 7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 88, 26 kDa
      Observed band size: 88 kDa
    • IHC image of CSB-PA814204LA01HU diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA814204LA01HU diluted at 1:300 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) NPAS4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    NPAS4
  • 別名:
    bHLH PAS type transcription factor NXF antibody; bHLHe79 antibody; Class E basic helix-loop-helix protein 79 antibody; HLH-PAS transcription factor NXF antibody; Le PAS antibody; limbic enhanced PAS protein antibody; neuronal PAS domain protein 4 antibody; Neuronal PAS domain-containing protein 4 antibody; Neuronal PAS4 antibody; NPAS4 antibody; NPAS4_HUMAN antibody; NXF antibody; PAS domain-containing protein 10 antibody; PASD10 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Neuronal PAS domain-containing protein 4 protein (445-585AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,NPAS4 Antibody (CSB-PA814204LA01HU),的標記方式是Non-conjugated。對于NPAS4 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA814204LB01HU NPAS4 Antibody, HRP conjugated ELISA
    FITC CSB-PA814204LC01HU NPAS4 Antibody, FITC conjugated
    Biotin CSB-PA814204LD01HU NPAS4 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late-response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal activity in a manner specific to their function within a circuit, thereby facilitating appropriate circuit responses to sensory experience. In excitatory neurons, activates transcription of BDNF, which in turn controls the number of GABA-releasing synapses that form on excitatory neurons, thereby promoting an increased number of inhibitory synapses on excitatory neurons. In inhibitory neurons, regulates a distinct set of target genes that serve to increase excitatory input onto somatostatin neurons, probably resulting in enhanced feedback inhibition within cortical circuits. The excitatory and inhibitory balance in neurons affects a number of processes, such as short-term and long-term memory, acquisition of experience, fear memory, response to stress and social behavior. Acts as a regulator of dendritic spine development in olfactory bulb granule cells in a sensory-experience-dependent manner by regulating expression of MDM2. Efficient DNA binding requires dimerization with another bHLH protein, such as ARNT, ARNT2 or BMAL1. Can activate the CME (CNS midline enhancer) element.
  • 基因功能參考文獻:
    1. NPAS4 is expressed in endothelial cells, regulates VE-cadherin expression and regulates sprouting angiogenesis. PMID: 28082451
    2. This review summarizes the current knowledge of the roles that Npas4 may play in neuroinflammation and ischemia. [review] PMID: 26690124
    3. we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain PMID: 24887558
    4. These results provide insight into the mechanisms of NPAS4/ARNT dimerisation and transcriptional activation. PMID: 24465693
    5. a novel NXF signaling system on neural gene promoter may be a molecular target of the adverse effects of Sim2 in the mental retardation of Down's syndrome PMID: 14701734

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Brain.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 18983

    OMIM: 608554

    KEGG: hsa:266743

    STRING: 9606.ENSP00000311196

    UniGene: Hs.256036



主站蜘蛛池模板: 99在线精品视频在线观看| 亚洲一区二区三区小说| 久久国产欧美日韩精品 | 国产肉体xxxx裸体137大胆 | 成人乱码一区二区三区av| 成熟丰满熟妇av无码区| 精品噜噜噜噜久久久久久久久| 免费视频国产在线观看| 成人三级无码视频在线观看| 国产精品久久久久久亚洲| 国产成人av综合久久| 被技师按摩到高潮的少妇| 色综合伊人丁香五月桃花婷婷| 人妻少妇精品视频二区| 久久人人做人人妻人人玩精品hd | 久久久肥妇熟女ⅹxxx毛片| 欧美成人一区二区三区片免费| 欧美老肥妇做爰bbww| 欧美性狂猛xxxxx深喉| 亚洲成年看片在线观看| 国产午夜激无码av毛片不卡| 亚洲一区二区女搞男| 在线天堂资源www在线污| 精品人妻无码区二区三区| 波多野结衣50连登视频| av无码人妻一区二区三区牛牛| 久九九久视频精品免费| 强行糟蹋人妻hd中文| 亚洲情xo亚洲色xo无码| 国产av久久久久精东av| 亚洲一区二区色情苍井空| 日本熟妇色一本在线观看| 中国人妻被两个老外三p| 东北妇女xx做爰视频| 99久久久无码国产精品6 | 玖玖资源站无码专区| 超碰国产精品久久国产精品99| 国产后进白嫩翘臀在线播放| 日本少妇浓毛bbwbbwbbw| 国产精品偷伦视频免费观看了| 国产av天堂无码一区二区三区|