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  4. NMT2 Antibody

NMT2 Antibody

  • 中文名稱：
    NMT2兔多克隆抗體
  • 貨號：
    CSB-PA158660
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA158660(NMT2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A549 cells, hela cells, Primary antibody: CSB-PA158660(NMT2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    EC 2.3.1.97 antibody; Glycylpeptide N tetradecanoyltransferase 2 antibody; Glycylpeptide N-tetradecanoyltransferase 2 antibody; Myristoyl CoA:protein N myristoyltransferase 2 antibody; Myristoyl-CoA:protein N-myristoyltransferase 2 antibody; N-myristoyltransferase 2 antibody; NMT 2 antibody; NMT2 antibody; NMT2_HUMAN antibody; Peptide N myristoyltransferase 2 antibody; Peptide N-myristoyltransferase 2 antibody; Type II N myristoyltransferase antibody; Type II N-myristoyltransferase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human NMT2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
  • 基因功能參考文獻：
    1. ligand binding properties of the NMT/ACBD6 complex can explain how the NMT reaction can proceed in the presence of the very abundant competitive substrate, C(16)-CoA. PMID: 26621918
    2. induction of NMT2 may play a central role in dioxin carcinogenicity. PMID: 11731439
    3. NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID: 16123142
    4. Involved in progression and regulation of telomerase PMID: 16364039
    5. Protein-protein interaction of NMTs revealed that m-calpain interacts with NMT1 while caspase-3 interacts with NMT2. PMID: 16530191
    6. Disruption of the gene for NMT2 by a t(8;10) translocation in a male with hypogonadism. PMID: 17568424
    7. Nef is preferentially myristoylated by NMT2, suggesting that selective inhibition of NMT2 may provide a novel means of blocking HIV virulence. PMID: 18089753

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  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    NMT family
  • 數據庫鏈接：

    HGNC: 7858

    OMIM: 603801

    KEGG: hsa:9397

    STRING: 9606.ENSP00000367407

    UniGene: Hs.60339



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