在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NMT1 Antibody

  • 中文名稱:
    NMT1兔多克隆抗體
  • 貨號:
    CSB-PA557232
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA557232(NMT1 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA557232(NMT1 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Alternative, short form NMT S antibody; EC 2.3.1.97 antibody; Glycylpeptide N tetradecanoyltransferase 1 antibody; Glycylpeptide N-tetradecanoyltransferase 1 antibody; Long form, NMT L antibody; Myristoyl CoA:protein N myristoyltransferase 1 antibody; Myristoyl-CoA:protein N-myristoyltransferase 1 antibody; N myristoyltransferase 1 antibody; NMT 1 antibody; NMT antibody; nmt1 antibody; NMT1_HUMAN antibody; Peptide N myristoyltransferase 1 antibody; Peptide N-myristoyltransferase 1 antibody; Type I N myristoyltransferase antibody; Type I N-myristoyltransferase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human NMT1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
  • 基因功能參考文獻:
    1. Genetic and pharmacologic evidence that inhibiting the N-myristoyltransferase NMT1 suppresses cell-cycle progression, proliferation, and malignant growth of prostate cancer cells. PMID: 29038344
    2. These observations point at a previously unrecognized contribution of calnexin to the retention of NMT1 at the ER membrane. PMID: 26603938
    3. findings suggest that both NMT1 and hnRNP A2/B1 take part in the regulation of HIV-1 RNA expression through their mutual opposite effects on the viral RNA expression in HIV-1-producing cells PMID: 26074144
    4. we propose a model of the Nef:NMT complex in which only the myristoyl moiety holds the two proteins together in complex and speculate that perhaps NMT chaperones Nef to the membrane and thereby protects the myristic acid group from the cytosol PMID: 21449607
    5. In this study, we found decreases in the mRNA levels of human NMT isoforms and the NMT activities in the course of HIV-1 infection in the human T-cell line PMID: 12220649
    6. role of HSC70 in the regulation of NMT PMID: 15156568
    7. NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID: 16123142
    8. Elevated N-myristoyltransferase activity is associated with oral squamous cell carcinoma PMID: 17549352
    9. N-myristoyltransferase may have a role in progression of colonic neoplasms PMID: 18021392
    10. Nef is preferentially myristoylated by NMT2, suggesting that selective inhibition of NMT2 may provide a novel means of blocking HIV virulence. PMID: 18089753
    11. These results strongly suggest that HIV-1 production is specifically associated with hNMT1, particularly hNMT1(L), but not with hNMT2 in vivo, contributing to the understanding of a step in HIV-1 replication. PMID: 18248763

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
  • 蛋白家族:
    NMT family
  • 組織特異性:
    Heart, gut, kidney, liver and placenta.
  • 數據庫鏈接:

    HGNC: 7857

    OMIM: 160993

    KEGG: hsa:4836

    STRING: 9606.ENSP00000258960

    UniGene: Hs.532790



主站蜘蛛池模板: 亚洲色成人网一二三区| 亚洲乱码av中文一区二区软件| 国产成人精品999视频| 女人被爽到高潮视频免费国产 | 午夜伦4480yy私人影院久久| 国自产拍偷拍精品啪啪av| 中文天堂资源在线www| 熟妇丰满多毛的大隂户| www国产亚洲精品久久| 米奇影院888奇米色99在线| 国产成人精品一区二区三区| 人妻中文无码久热丝袜| 国模大尺度啪啪| 天天狠天天透天干天天| 亚洲卡一卡二新区| 久久人妻av无码中文专区| 免费国产a国产片高清| 亚洲乱色伦图片区小说| 国产免费踩踏调教视频| 性做久久久久久免费观看| 人人妻人人澡人人爽国产一区| 纯肉无遮挡无码日本动漫| 国产精品992tv在线观看| 免费欧洲美女牲交视频| 寂寞少妇做spa按摩无码| 国产精品久久久久7777按摩| 国产山东熟女48嗷嗷叫| 四虎国产精品永久在线观看| 国产成人免费ā片在线观看| 久久天天躁夜夜躁狠狠综合| 亚洲熟女av综合网五月| 乱熟女高潮一区二区在线| 亚洲综合一区二区三区四区五区| 国产精品真实灌醉女在线播放| 人妻无码久久一区二区三区免费| 99久久综合狠狠综合久久止 | 精品人妻伦一二三区久久| 成人欧美一区二区三区a片| 亚洲欧洲成人a∨在线| 俄罗斯丰满熟妇hd| 色欲天天婬色婬香综合网完整 |