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  4. NME7 Antibody, FITC conjugated

NME7 Antibody, FITC conjugated

  • 中文名稱：
    NME7兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA897289LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NME7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NME7
  • 別名：
    MN23H7 antibody; NDK 7 antibody; NDK7_HUMAN antibody; NDP kinase 7 antibody; nm23 H7 antibody; nm23-H7 antibody; NME/NM23 family member 7 antibody; Nme7 antibody; Non metastatic cells 7 protein expressed in (nucleoside diphosphate kinase) antibody; Nucleoside diphosphate kinase 7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Nucleoside diphosphate kinase 7 protein (1-150AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  • 基因功能參考文獻：
    1. Study provides evidence that the deleterious mutation in NME7, which results in deletion of amino acids necessary for its interaction with Gamma-tubulin ring complex associated with impaired left-right asymmetry manifested by Situs Inversus Totalis. PMID: 27060491
    2. RNA-seq analysis shows vast differences between the parent FGF2 grown, primed state cells, and NME7AB converted cells, but similarities to altered gene expression patterns reported by others generating naive-like stem cells via the use of biochemical inhibitors PMID: 26749426
    3. NME7 functions in the gamma-tubulin ring complex in a kinase-dependent manner to facilitate microtubule nucleation. PMID: 24807905
    4. Compared with wild-type betagamma nucleoside diphosphate kinase overexpression of Gbeta nucleoside diphosphate kinase suppressed basal cAMP formation up to 55%. PMID: 17363702
  • 蛋白家族：
    NDK family
  • 數據庫鏈接：

    HGNC: 20461

    OMIM: 613465

    KEGG: hsa:29922

    STRING: 9606.ENSP00000356785

    UniGene: Hs.706952



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