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  4. NMB Antibody

NMB Antibody

  • 中文名稱：
    NMB兔多克隆抗體
  • 貨號：
    CSB-PA015880GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    NMB
  • 別名：
    NMB antibody; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human NMB
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Stimulates smooth muscle contraction in a manner similar to that of bombesin.
  • 基因功能參考文獻：
    1. Genetic clues to the mechanism by which MC4R, FTO, and NMB influences changes in BMI and obesity. PMID: 27634552
    2. Rs2292462 was associated with left ventricular hypertrophy in type 2 diabetic patients. PMID: 23879873
    3. There was no association between eating behaviour traits, or anthropometric variables, and NMB p.P73T polymorphism. PMID: 21527296
    4. TT genotype of the NMB rs3809508 polymorphism was associated with a higher risk of obesity and moreover, the effects of this polymorphism on anthropometric values were influenced by the maternal educational level. PMID: 20010906
    5. lysosomal degradation of neuromedin B is dependent on tripeptidyl peptidase-I PMID: 15158442
    6. NMB and its receptor are coexpressed by proliferating cells in which they act in an autocrine fashion with similar and modest potency in both normal and malignant colonic epithelial cells. PMID: 15528253
    7. Associated with eating behaviors PMID: 15585758
    8. REsults describe the expression of neuromedin B in adipose tissue and its regulation by changes in energy balance. PMID: 17766645
    9. No significant differences in the genotype distribution were demonstrated between normal weight and overweight/obese subjects PMID: 18271693

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Bombesin/neuromedin-B/ranatensin family
  • 數據庫鏈接：

    HGNC: 7842

    OMIM: 162340

    KEGG: hsa:4828

    STRING: 9606.ENSP00000378089

    UniGene: Hs.386470



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