在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NINJ1 Antibody, Biotin conjugated

  • 中文名稱:
    NINJ1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA856441LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) NINJ1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    NINJ1; Ninjurin-1; Nerve injury-induced protein 1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ninjurin-1 protein (1-80AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Homophilic transmembrane adhesion molecule involved in various processes such as inflammation, cell death, axonal growth, cell chemotaxis and angiogenesis. Promotes cell adhesion by mediating homophilic interactions via its extracellular N-terminal adhesion motif (N-NAM). Involved in the progression of the inflammatory stress by promoting cell-to-cell interactions between immune cells and endothelial cells. Involved in leukocyte migration during inflammation by promoting transendothelial migration of macrophages via homotypic binding. Promotes the migration of monocytes across the brain endothelium to central nervous system inflammatory lesions. Acts as a regulator of Toll-like receptor 4 (TLR4) signaling triggered by lipopolysaccharide (LPS) during systemic inflammation; directly binds LPS. Acts as a mediator of both programmed and necrotic cell death. Plays a key role in the induction of plasma membrane rupture during programmed and necrotic cell death: oligomerizes in response to death stimuli to mediate plasma membrane rupture (cytolysis), leading to release intracellular molecules named damage-associated molecular patterns (DAMPs) that propagate the inflammatory response. Plays a role in nerve regeneration by promoting maturation of Schwann cells. Acts as a regulator of angiogenesis. Promotes the formation of new vessels by mediating the interaction between capillary pericyte cells and endothelial cells. Promotes osteoclasts development by enhancing the survival of prefusion osteoclasts. Also involved in striated muscle growth and differentiation.; Secreted form generated by cleavage, which has chemotactic activity. Acts as an anti-inflammatory mediator by promoting monocyte recruitment, thereby ameliorating atherosclerosis.
  • 基因功能參考文獻:
    1. Data show that Ninj1 assembles into a homomeric protein complex and that N-glycosylation is a prerequisite for Ninj1 homomer assembly. PMID: 28067406
    2. Ninj1 suppresses migration, invasion and metastasis of lung cancer via inhibition of the IL-6 signaling pathway in vitro and in vivo. PMID: 26815582
    3. High ninjurin 1 expression is associated with Prostate Cancer. PMID: 28373430
    4. Ninj1 expression was detected in both HSMCs and HUVECs, and was higher in the former. Ninj1 expression was enhanced by hypoxia in HUVECs. PMID: 25766274
    5. Ninj1 modulates TLR4 signaling, which itself plays a major role in systemic inflammatory response syndrome and sepsis. PMID: 25860173
    6. The NINJ1 gene polymorphism plays an important role in nerve degeneration in leprosy patients. PMID: 22326538
    7. Data show an important cell-specific role for Ninjurin-1 in the transmigration of inflammatory APCs across the BBB. PMID: 22162058
    8. Ninjurin1 is able to induce the senescence program. Ninjurin1 may be involved in the regulation of cellular senescence in the liver during carcinogenesis. PMID: 15464245
    9. Our data suggests that Ninjurin 1 asp110ala SNP could be a valuable genetic marker of nerve damage in leprosy. PMID: 17825431

    顯示更多

    收起更多

  • 亞細胞定位:
    [Ninjurin-1]: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, synaptic cell membrane; Multi-pass membrane protein.; [Secreted ninjurin-1]: Secreted.
  • 蛋白家族:
    Ninjurin family
  • 組織特異性:
    Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.
  • 數據庫鏈接:

    HGNC: 7824

    OMIM: 602062

    KEGG: hsa:4814

    STRING: 9606.ENSP00000364595

    UniGene: Hs.494457



主站蜘蛛池模板: 69天堂人成无码免费视频| 精品视频在线观自拍自拍| 国产三级在线观看播放| 十八禁av无码免费网站| 两个人看的www视频免费完整版| 中文字幕精品一区二区精品| 在线成人a毛片免费播放| 久久婷婷色综合老司机| 精品av综合导航| 女人裸体性做爰视频| 成 人 亚洲 综合天堂| 国产传媒麻豆剧精品av| 麻豆国产人妻欲求不满谁演的| 免费大黄网站在线观| 日韩 国产 变态另类 欧美| 中文字幕精品久久久久人妻红杏| 日韩成人大屁股内射喷水| 国产98色在线 | 国产| 午夜福利麻豆国产精品| 国产片av片永久免费观看| 国产精品99久久久久久久女警 | 久久久久无码国产精品不卡| 国产人澡人澡澡澡人碰视频 | 18禁黄污无遮挡无码网站| 国产亚洲精品欧洲在线观看| 国产一线二线三线女| 国产综合色在线视频区| 国产无遮挡乱子伦免费精品 | 国产乱子伦农村xxxx| 中文人妻无码一区二区三区信息| 亚洲日韩看片无码电影| 丁香五月亚洲中文字幕| 少妇群交换bd高清国语版| 精品免费久久久久久久| 狠狠躁夜夜躁人人爽天天| 亚洲 卡通 欧美 制服 中文| 无码国内精品久久综合88| 丰满少妇被猛烈进入高清播放| 十八禁真人啪啪免费网站| 亚洲免费视频免在线观看| 男男啪啪激烈高潮cc漫画免费|