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  4. NGFRAP1 Antibody

NGFRAP1 Antibody

  • 中文名稱：
    NGFRAP1兔多克隆抗體
  • 貨號：
    CSB-PA015781GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Bex antibody; BEX3 antibody; BEX3_HUMAN antibody; Brain expressed X linked 3 (mouse) homolog antibody; brain expressed; X-linked 3 antibody; Brain-expressed X-linked gene 3 antibody; Brain-expressed X-linked protein 3 antibody; DXS6984E antibody; HGR74 antibody; NADE antibody; Nerve growth factor receptor (TNFRSF16) associated protein 1 antibody; Nerve growth factor receptor associated protein 1 antibody; Nerve growth factor receptor-associated protein 1 antibody; NGFR-associated protein 1 antibody; NGFRAP1 antibody; Ovarian granulosa cell 13.0 kDa protein HGR74 antibody; ovarian granulosa cell protein (13kD) antibody; Ovarian granulosa cell protein antibody; p75NTR associated cell death executor antibody; p75NTR-associated cell death executor antibody; Protein BEX3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human NGFRAP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
  • 基因功能參考文獻：
    1. Results showed that BEX3 was overexpressed in nasopharyngeal carcinoma (NPC), and indicated a unique functional role of BEX3 in mediating the sensitivity of NPC cells to cisplatin. PMID: 28083995
    2. Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis PMID: 11830582
    3. suppresses cell growth in vivo, when expressed in cultured cells PMID: 12739005
    4. DRG-1 may contribute to the dopamine-induced cell growth, which is negatively regulated by NADE PMID: 16777077
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    BEX family
  • 組織特異性：
    Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
  • 數據庫鏈接：

    HGNC: 13388

    OMIM: 300361

    KEGG: hsa:27018

    STRING: 9606.ENSP00000299872

    UniGene: Hs.448588



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