在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NFYB Antibody

NFYB Antibody

  • 中文名稱：
    NFYB兔多克隆抗體
  • 貨號：
    CSB-PA003425
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 293 cells using NF-YB Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    CAAT box DNA binding protein subunit B antibody; CAAT box DNA-binding protein subunit B antibody; CBF A antibody; CBF B antibody; CCAAT binding transcription factor subunit A antibody; HAP 3 antibody; HAP3 antibody; NF Y protein chain B antibody; NF YB antibody; NF-YB antibody; NFYB antibody; NFYB_HUMAN antibody; Nuclear transcription factor Y beta antibody; Nuclear transcription factor Y subunit B antibody; Nuclear transcription factor Y subunit beta antibody; Transcription factor NF Y B subunit antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human NF-YB.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
  • 基因功能參考文獻：
    1. The nuclear transcription factor Y subunit beta (NFYB)-E2F transcription factor 1 (E2F1) pathway displays a crucial role in the chemoresistance ofoxaliplatin-resistant colorectal cancer (OR-CRC) by inducing the expression and activation of checkpoint kinase 1 (CHK1), suggesting a possible therapeutic target for oxaliplatin resistance in CRC. PMID: 29203250
    2. NF-YB transcription factor was identified as a novel direct E2F1 target. PMID: 26039627
    3. The NF-Y complex is asymmetric, with NF-YB binding approximately 15 bp downstream from the CCAAT motif. PMID: 23595228
    4. Transcriptional repression mediated by IER5 regulates Cdc25B expression levels via the release of NF-YB and p300 in acute myeloid leukemia. PMID: 22132193
    5. NF-Y acts upstream of H3K4me3 deposition by recruiting Ash2L PMID: 21445285
    6. MicroRNA-485-3p regulates drug responsiveness by decreasing nuclear factor-YB expression, which in turn negatively regulates DNA topoisomerase IIalpha. PMID: 21252292
    7. The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y. PMID: 12401788
    8. CBF/NF-Y proteins regulate the transcription of COL11A1 by directly binding to the ATTGG sequence in the proximal promoter region PMID: 12805369
    9. Co-operative functional interactions between Sp1 & NF-Y are required to direct the activity of the ATP1A3 promoter predominantly in neuronal cells. PMID: 15462673
    10. trichostatin A activates the transcription of TSP1 gene through the binding of transcription factor CBF to CCAAT box and the enhanced histone acetylation. PMID: 18275041
    11. CBF-A is a novel transacting factor required for cytoplasmic mRNA transport and localization PMID: 18480411

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    NFYB/HAP3 subunit family
  • 數據庫鏈接：

    HGNC: 7805

    OMIM: 189904

    KEGG: hsa:4801

    STRING: 9606.ENSP00000240055

    UniGene: Hs.84928



主站蜘蛛池模板： 九九热久久只有精品2| 亚洲va久久久噜噜噜久久天堂| 国产亚洲精品久久yy5099| 日本少妇浓毛bbwbbwbbw| 欧美黑人又粗又大的性格特点| 人妻丰满av无码久久不卡 | 一本一本久久a久久综合精品 | 国产精品无码一区二区在线观一| 曰韩内射六十七十老熟女影视| 国产又猛又黄又爽| 国产婷婷亚洲999精品小说| 2019一級特黃色毛片免費看| 国产色视频一区二区三区qq号| 亚洲国产综合精品 在线 一区| 国产精品特黄aaaa片在线观看| 天堂在线.www天堂在线资源| 97久久精品人人澡人人爽| 国产精品高潮呻吟av久久无吗| 中国china体内裑精亚洲日本| 国产香蕉尹人在线观看视频| 久久精品国产精品亚洲| 国产精品99久久免费| 亚洲日本va中文字幕人妖| 男人用嘴添女人下身免费视频| 无码精品一区二区三区在线| 天天做av天天爱天天爽| 137肉体摄影日本裸交| 国产亚洲精品久久久久婷婷瑜伽| 午夜高清在线无码| 1313午夜精品理论片| 亚洲午夜成人av电影| 99精品国产在热久久| 亚洲精品久久久久久久久久久捆绑 | 娇妻被黑人粗大高潮白浆| 国产欧美日韩综合在线成| 人与嘼av免费| 脱岳裙子从后面挺进去在线观看| 华人在线亚洲欧美精品| 日日摸处处碰夜夜爽| 久久精品中文字幕无码绿巨人| 日本精品αv中文字幕|