在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NFKBIB Antibody

  • 中文名稱:
    NFKBIB兔多克隆抗體
  • 貨號:
    CSB-PA015762GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    I kappa B beta antibody; I-kappa-B-beta antibody; IkappaBbeta antibody; IKB beta antibody; IkB-B antibody; IkB-beta antibody; IKBB antibody; IKBB_HUMAN antibody; IkBbeta antibody; NF kappa BIB antibody; NF-kappa-B inhibitor beta antibody; NF-kappa-BIB antibody; Nfkbib antibody; Thyroid receptor interacting protein 9 antibody; Thyroid receptor-interacting protein 9 antibody; TR interacting protein 9 antibody; TR-interacting protein 9 antibody; TRIP-9 antibody; TRIP9 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human NFKBIB
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • 基因功能參考文獻:
    1. The subcellular distributions of IkappaB and NFkappaB are indicative of carcinogenesis. Inhibition of XPO1 results in intranuclear retention of IkappaB, which inhibits NFkappaB and thereby provides a novel mechanism for drug therapy in sarcoma. This effect can be further enhanced in relatively selinexor-resistant sarcoma cell lines by pretreatment with the proteasome inhibitor carfilzomib. PMID: 28314790
    2. data suggest that miRNA-4776 modulates Influenza A virus production in infected cells through NFKBIB expression, possibly through the modulation of NF-kappaB. PMID: 28448456
    3. our data establish the importance of a novel tumor suppressive IKBB gene in abrogating angiogenesis in NPC via the NF-kappaB signalling pathway. PMID: 26227166
    4. NFKBIBrs3136641TT single nucleotide polymorphism was associated with a significantly decreased risk of developing wheezing. PMID: 25326706
    5. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis PMID: 12475944
    6. VEGF increased Mn-superoxide dismutase promoter activity, an effect that was dependent on a second intronic NF-kappaB consensus motif. PMID: 15308628
    7. data indicate that inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta PMID: 15919917
    8. None of the NFKBIB SNPs are associated with pneumococcal susceptibility. PMID: 17463416
    9. increased I-kappaBbeta expression reversed NF-kappaB activation in cancer cells, compensating for the loss of I-kappaBalpha via TGase 2 polymerization. PMID: 18950638

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    NF-kappa-B inhibitor family
  • 組織特異性:
    Expressed in all tissues examined.
  • 數據庫鏈接:

    HGNC: 7798

    OMIM: 604495

    KEGG: hsa:4793

    STRING: 9606.ENSP00000312988

    UniGene: Hs.9731



主站蜘蛛池模板: 国产做爰xxxⅹ高潮视频12p| 欧美情侣性视频| 波多野结衣乳巨码无在线观看| 久久精品99久久香蕉国产色戒| 日本少妇被黑人xxxxx| 国产精品亚洲а∨天堂免下载| 中老年熟妇激情啪啪大屁股| 国内精品久久久久久不卡影院| 射死你天天日| 成人午夜无码专区性视频性视频| 日产精品一卡2卡三卡4乱码| 亂倫近親相姦中文字幕| 欧美丰满熟妇bbb久久久| 久久婷婷五月综合色俺也想去 | 日本在线a一区视频| 日韩 高清 无码 人妻| 无码人妻av一区二区三区波多野| 午夜男女爽爽影院免费视频下载| 无码国产乱人伦偷精品视频| 国产成人无码a区在线| 牲高潮99爽久久久久777| 免费国产裸体美女视频全黄| 播放男人添女人下边视频| 国产玉足脚交极品在线播放| 日本丰满老妇bbw| 在线成人精品国产区免费| а√天堂资源官网在线资源| 97精品国自产在线偷拍| 777米奇色狠狠俺去啦奇米77| 久久精品aⅴ无码中文字字幕蜜桃 午夜成人鲁丝片午夜精品 | 亚洲中文精品久久久久久| 四虎国产精品永久在线观看| 无遮挡又爽又刺激的视频| 亚洲 综合 欧美 动漫 丝袜| 东京一本一道一二三区| 中文字字幕人妻中文| 久久午夜电影网| 成人精品免费视频在线观看| 日韩欧美亚洲综合久久影院| 无码人妻精品一区二区三区66| 中文字幕亚洲精品乱码|