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  4. NETO1 Antibody, Biotin conjugated

NETO1 Antibody, Biotin conjugated

  • 中文名稱：
    NETO1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA840571LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NETO1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NETO1
  • 別名：
    AI851453 antibody; BCTL1 antibody; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody; BTCL1 antibody; C130005O10Rik antibody; FLJ41325 antibody; Neto1 antibody; NETO1_HUMAN antibody; Neuropilin and tolloid like 1 antibody; Neuropilin and tolloid-like protein 1 antibody; RGD1566269 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Neuropilin and tolloid-like protein 1 protein (367-507AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
  • 基因功能參考文獻：
    1. Neto1 is concluded to be a component of amyloid precursor protein /NMDA receptor trafficking complexes PMID: 23621516
    2. no evidence for the association of NETO1 with schizophrenia in the Japanese population PMID: 22205981
    3. Mouse neto1 plays a critical role in spatial learning and memory through the regulation of NMDAR subunit abundance at synapses. PMID: 19243221
  • 亞細胞定位：
    [Isoform 2]: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 1]: Secreted.
  • 組織特異性：
    Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain.
  • 數據庫鏈接：

    HGNC: 13823

    OMIM: 607973

    KEGG: hsa:81832

    STRING: 9606.ENSP00000313088

    UniGene: Hs.465407



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