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NEMF Antibody

  • 中文名稱：
    NEMF兔多克隆抗體
  • 貨號：
    CSB-PA003494
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 3T3 cells using NY-CO-1 Polyclonal Antibody
    • Western Blot analysis of NIH-3T3 cells using NY-CO-1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    NEMF
  • 別名：
    1500011I12Rik antibody; 4933405E14Rik antibody; Antigen NY-CO-1 antibody; FLJ10051 antibody; Nemf antibody; NEMF_HUMAN antibody; Nuclear export mediator factor Nemf antibody; NY CO 1 antibody; SDCCAG1 antibody; SDCG1 antibody; Serologically defined colon cancer antigen 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human NY-CO-1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex. May indirectly play a role in nuclear export.
  • 基因功能參考文獻：
    1. Results show that Listerin specificity for nascent chain-60S complexes depends on nuclear export mediator factor. PMID: 25578875
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    NEMF family
  • 組織特異性：
    Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
  • 數據庫鏈接：

    HGNC: 10663

    OMIM: 608378

    KEGG: hsa:9147

    STRING: 9606.ENSP00000298310

    UniGene: Hs.655964



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