在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NEGR1 Antibody

NEGR1 Antibody

  • 中文名稱：
    NEGR1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA003394
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using NEGR1 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    NEGR1
  • 別名：
    NEGR1 antibody; IGLON4 antibody; UNQ2433/PRO4993 antibody; Neuronal growth regulator 1 antibody; IgLON family member 4 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human NEGR1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain.
  • 基因功能參考文獻(xiàn)：
    1. Our results indicate a possible contribution of CNVs in LEPR, NEGR1, ARHGEF4, and CPXCR1 and the intergenic regions 12q15c, 15q21.1a, and 22q11.21d to the development of obesity, particularly abdominal obesity in Mexican children. PMID: 28428959
    2. NEGR1, strong candidate gene, associated with clinical features of Depression (e.g., earlier age at onset and recurrent and more severe forms of Depression). Gene expression patterns in the prefrontal and anterior cingulate cortex most closely matched the genetic findings. PMID: 28969442
    3. Single nucleotide polymorphism in NEGR1 gene is associated with major depressive disorder. PMID: 27479909
    4. Significant associations were identified at 3.5 years old for TMEM18 rs6548238, NEGR1 rs2815752, BDNF rs10767664 and rs6265 (1 year old and 3.5 years old) with anthropometric phenotypes PMID: 27005443
    5. NEGR1 interacts with NPC2 and increases its protein stability; it has a role in obesity PMID: 27940359
    6. Genetic variants associated with BMI and WHR in adults influence growth patterns and general and abdominal fat development from early childhood onwards. PMID: 25640768
    7. We observed novel selection signals in CDKAL1 and NEGR1, well-known diabetes and obesity susceptibility genes PMID: 25370040
    8. NEGR1 could be an important locus influencing certain personality dimensions in BN patients. PMID: 25245582
    9. First study to find an association between an obesity risk gene and differences in white matter integrity. As our subjects were young and healthy, our results suggest that NEGR1 has effects on brain structure independent of its effect on obesity. PMID: 25072390
    10. Data indicate strong associations with severe obesity for single nucleotide polymorphism (SNP) rs9939609 within the FTO gene and SNP rs2815752 near the NEGR1 gene. PMID: 23950990
    11. Results imply a regulatory role for TMEM18, BDNF, MTCH2 and NEGR1 in adipocyte differentiation and biology. In addition, we show a variation of MAF expression during adipogenesis, while NPC1, PTER and SH2B1 were not regulated. PMID: 23229156
    12. Our study supports earlier reports of SH2B1 to be of importance in insulin sensitivity and, in addition, suggests potential roles of NEGR1 and MTCH2. PMID: 22443470
    13. Meta-analysis of 4992 subjects revealed seven SNPs near four loci, including NEGR1, TMEM18, SH2B1 /ATP2A1 and MC4R, showing significant association at 0.005 PMID: 21750520
    14. Gene-treatment interactions were observed for long-term (NEGR1 rs2815752, Pmetformin*SNP = 0.028; FTO rs9939609, Plifestyle*SNP = 0.044) weight loss. PMID: 22179955
    15. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. PMID: 22360420
    16. Data suggest that in addition to its reported role in the brain, NEGR1 is also expressed in subcutaneous adipose tissue and acts as a central 'hub' in an obesity-related transcript network. PMID: 21427694
    17. The results of these studies provide supporting evidence for MYEOV and NEGR1 as gene targets of 11q13 gains and 1p31 deletions in a neuroblastoma subset. PMID: 21624008
    18. Observational study of gene-disease association. (HuGE Navigator) PMID: 20712903
    19. Observational study of gene-disease association. (HuGE Navigator) PMID: 20724581
    20. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20725061
    21. Observational study of gene-disease association. (HuGE Navigator) PMID: 20816152
    22. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    23. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20571754
    24. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
    25. Observational study of gene-disease association. (HuGE Navigator) PMID: 20816195
    26. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    27. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20386550
    28. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20520848
    29. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20215397
    30. Observational study of gene-disease association. (HuGE Navigator) PMID: 19746409
    31. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 19812171
    32. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851340
    33. Observational study of gene-disease association. (HuGE Navigator) PMID: 19910938
    34. Observational study of gene-disease association. (HuGE Navigator) PMID: 19692490
    35. Observational study of gene-disease association. (HuGE Navigator) PMID: 19164386
    36. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19079261

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Immunoglobulin superfamily, IgLON family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17302

    OMIM: 613173

    KEGG: hsa:257194

    STRING: 9606.ENSP00000350364

    UniGene: Hs.146542



主站蜘蛛池模板： 亚洲精品一区二区| 狠狠久久噜噜熟女| 中文幕无线码中文字夫妻| 呻吟国产av久久一区二区| 欧美日韩在手机线旡码可下载| 2021麻豆剧传媒一二三区| 国产精品无码一区二区在线观一| 久久综合亚洲色一区二区三区 | 日本精品aⅴ一区二区三区| 午夜亚洲福利在线老司机| 波多野结衣av手机在线观看 | 2019一級特黃色毛片免費看| 久久久久国色av免费看| 51视频国产精品一区二区| 国产成人综合在线女婷五月99播放 | 日本vs亚洲vs韩国一区三区| 亚洲国产成人一区二区三区| 亚洲国产av美女网站| 欧美在线看片a免费观看| 亚洲综合最新无码专区| 韩国国内大量揄拍精品视频| 成人毛片100免费观看| 亚洲精品国产精品国自产| 久久久久久久久免费看无码| 亚洲日韩日本中文在线| 久久精品www人人做人人爽| 自拍偷自拍亚洲精品播放| 亚洲熟妇国产熟妇肥婆| 亚洲中文字幕无码永久| 国产内射xxxxx在线| 精品国产一区二区三区四区| 国产精品毛片一区二区| 久久激情日本亚洲欧洲国产中文 | 亚洲国产精品一区二区动图| 久久久久久亚洲综合影院| 欧美超级乱婬视频播放 | 青草青草久热国产精品| 久久久久国色av∨免费看| 欧美精品一区二区黄a片| 午夜射精日本三级| 免费无码又爽又刺激一高潮|