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  4. NDUFS8 Antibody, Biotin conjugated

NDUFS8 Antibody, Biotin conjugated

  • 中文名稱：
    NDUFS8兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA015667LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NDUFS8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CI 23kD antibody; CI-23kD antibody; Complex I 23kD antibody; Complex I-23kD antibody; EC 1.6.5.3 antibody; EC 1.6.99.3 antibody; Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8 antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8; mitochondrial antibody; NADH ubiquinone oxidoreductase 23 kDa subunit antibody; NADH-ubiquinone oxidoreductase 23 kDa subunit antibody; NDUFS8 antibody; NDUS8_HUMAN antibody; TYKY antibody; TYKY subunit antibody; Ubiquinoneiron sulfur protein 8; mitochondrial precursor antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial protein (35-210AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
  • 基因功能參考文獻：
    1. Results show that NDUFS8 protein and mRNA levels are up-regulated in lung neoplasm and correlate with poor overall survival. PMID: 27516145
    2. 2 new mutations (P85L upstream from the 2 cysteine motifs that coordinate the two [4Fe-4S] clusters which generate the complex I N2 clusters, & R138H between them)suggest that this subunit is essential for either the assembly or stability of complex I. PMID: 15159508
  • 相關疾病：
    Leigh syndrome (LS)
  • 亞細胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Complex I 23 kDa subunit family
  • 組織特異性：
    Expressed in all tissues with the highest level in heart and skeletal muscle and the lowest level in lung.
  • 數據庫鏈接：

    HGNC: 7715

    OMIM: 256000

    KEGG: hsa:4728

    STRING: 9606.ENSP00000315774

    UniGene: Hs.90443



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