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  4. NDUFS6 Antibody

NDUFS6 Antibody

  • 中文名稱：
    NDUFS6兔多克隆抗體
  • 貨號：
    CSB-PA020046
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    BC059730 antibody; CI 13kA antibody; CI 13kD A antibody; CI-13kD-A antibody; CI13KDA antibody; Complex I 13kD A antibody; Complex I 13kDa subunit A antibody; Complex I mitochondrial respiratory chain 13 kD subunit antibody; Complex I-13kD-A antibody; IP13 antibody; MGC107676 antibody; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH coenzyme Q reductase) antibody; NADH dehydrogenase [ubiquinone] iron sulfur protein 6, mitochondrial antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial antibody; NADH ubiquinone oxidoreductase 13 kDa A subunit antibody; NADH-ubiquinone oxidoreductase 13 kDa-A subunit antibody; NADH:ubiquinone oxidoreductase NDUFS6 subunit antibody; NADH:ubiquinone oxidoreductase subunit S6 antibody; Ndufs6 antibody; NDUS6_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human NDUFS6.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 基因功能參考文獻：
    1. CD147 appears to regulate complex I activity and apoptosis in malignant melanoma cells by interacting with mitochondrial NDUFS6. PMID: 25470292
    2. NDUFS6, a complex I subunit gene not previously associated with complex I deficiency, was grossly underexpressed in t patient cell lines. PMID: 15372108
    3. NDUFS6 is required for the assembly and stabilization of a portion of complex I that contains a number of subunits. PMID: 17438127
  • 相關疾病：
    Mitochondrial complex I deficiency (MT-C1D)
  • 亞細胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Complex I NDUFS6 subunit family
  • 數據庫鏈接：

    HGNC: 7713

    OMIM: 252010

    KEGG: hsa:4726

    STRING: 9606.ENSP00000274137

    UniGene: Hs.408257



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