在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NDUFA1 Antibody

NDUFA1 Antibody

  • 中文名稱：
    NDUFA1兔多克隆抗體
  • 貨號：
    CSB-PA271484
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA271484(NDUFA1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA271484(NDUFA1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; Complex I-MWFE; CI-MWFE; NADH-ubiquinone oxidoreductase MWFE subunit
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human NDUFA1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 基因功能參考文獻：
    1. Results from a study on gene expression variability markers in early-stage human embryos shows that NDUF1A is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. The gene signature of OPA1, CTSA, NDUFA1, STK10 and PRDX1 was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls. PMID: 27177495
    3. Fanconi anemia complementation group A mutants show defective respiration through Complex I, diminished ATP production and metabolic sufferance with an increased AMP/ATP ratio. PMID: 23791750
    4. Heterozygous mutation in the X chromosomal NDUFA1 gene in a girl with complex I deficiency PMID: 21596602
    5. Mutations in the NDUFA1 gene is linked to a delayed mitochondrial network recovery in OXPHOS disorders. PMID: 20153825
    6. Species-specific and mutant MWFE proteins effect on the assembly of a functional mammalian mitochondrial complex I. PMID: 11937507
    7. A family-based association study finds that the NDUFA1 gene is unlikely to harbor a major visual loss susceptibility locus for Leber hereditary optic neuropathy. PMID: 12084895
    8. Oxidative stress and partial deficiencies of mitochondrial complex I are key factors in the pathogenesis of Parkinson's disease. (REVIEW) PMID: 15038604
    9. Suppression of NDUFA1 expression could represent a key pathogenic mechanism in the development of basal cell carcinoma PMID: 15854127
    10. Two novel p.Gly8Arg and p.Arg37Ser hemizygous mutations in NDUFA1 were identified in two unrelated male patients presenting with Leigh's syndrome and with myoclonic epilepsy and developmental delay. PMID: 17262856
    11. hypothesize that the novel G32R mutation in NDUFA1 is causing complex I deficiency either by itself or in synergy with additional mtDNA variants PMID: 19185523

    顯示更多

    收起更多

  • 相關疾病：
    Mitochondrial complex I deficiency (MT-C1D)
  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
  • 蛋白家族：
    Complex I NDUFA1 subunit family
  • 組織特異性：
    Primarily expressed in heart and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 7683

    OMIM: 252010

    KEGG: hsa:4694

    STRING: 9606.ENSP00000360492

    UniGene: Hs.534168



主站蜘蛛池模板： 无码国产精品一区二区免费16| 欧美制服丝袜人妻另类| 麻豆文化传媒精品一区观看| 亚洲国产天堂久久久久久| 亚洲国产欧美在线观看片不卡| 免费无码av一区二区三区 | 日韩成人一区二区三区在线观看 | 精品系列无码一区二区三区| 又大又粗又长的高潮视频| 亚洲丰满熟女一区二区v| 中国大陆高清aⅴ毛片| 在线观看免费视频污网站| 麻豆人妻无码性色av专区 | 欧美 在线 成 人怡红院| 精品亚洲国产成人av不卡 | 蜜桃mv在线播放免费观看视频 | av无码av不卡一区二区| 人人插人人插人人爽| 成人综合婷婷国产精品久久| 亚洲中文字幕伊人久久无码| 男人边吃奶边做好爽免费视频| 精品深夜av无码一区二区| 亚洲一本大道av久在线播放| 久久ee热这里只有精品| gv天堂gv无码男同在线观看| 99久久免费精品高清特色大片| 国内裸体无遮挡免费视频| 97se亚洲国产综合自在线| 成熟妇人a片免费看网站| 亚洲日本中文字幕天天更新 | 三个男人躁我一个爽视频免费 | 国内精品伊人久久久久影院麻豆| 无码专区—va亚洲v专区vr| 久久狼人大香伊蕉国产| 亚洲色一区二区三区四区| 欧美人与动欧交视频| 亚洲中文字幕在线精品2021| 少妇高潮太爽了在线视频| 国产69精品久久久久久久| 无线日本视频精品| 国产精品一区二区 尿失禁|