在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NCKIPSD Antibody

NCKIPSD Antibody

  • 中文名稱：
    NCKIPSD兔多克隆抗體
  • 貨號：
    CSB-PA015534GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    NCKIPSD
  • 別名：
    54 kDa VacA-interacting protein antibody; 54 kDa vimentin-interacting protein antibody; 90 kDa SH3 protein interacting with Nck antibody; AF3p21 antibody; dia interacting protein antibody; Dia-interacting protein 1 antibody; Diaphanous protein-interacting protein antibody; DIP antibody; DIP-1 antibody; DIP1 antibody; NCK interacting protein with SH3 domain antibody; NCK-interacting protein with SH3 domain antibody; Nckipsd antibody; ORF1 antibody; SH3 adapter protein SPIN90 antibody; SH3 protein interacting with Nck 90 kDa antibody; SPIN90 antibody; SPN90_HUMAN antibody; VIP54 antibody; WASLBP antibody; WASP-interacting SH3-domain protein antibody; WISH antibody; wiskott- Aldrich syndrome protein-interacting protein antibody; Wiskott-Aldrich syndrome protein-interacting protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human NCKIPSD
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo. In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42. May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.
  • 基因功能參考文獻：
    1. Low SPIN90 expression is associated with Breast Cancer. PMID: 28652253
    2. findings suggest that SPIN90 contributes to the formation and movement of endosomal vesicles, and modulates the stability of EGFR protein, which affects cell cycle progression PMID: 24340049
    3. SPIN90 dephosphorylation is a prerequisite step for releasing cofilin so that cofilin can adequately sever actin filaments into monomeric form. PMID: 23765104
    4. Findings show that SPIN90 modulates synaptic activity in neurons as a result of its phosphorylation. PMID: 23342115
    5. Dia2 and DIP co-tether to nascent blebs and this linkage is required for bleb formation. PMID: 23024796
    6. the interaction of the betaPIX.WASP.SPIN90 complex with Nck is crucial for stable cell adhesion and can be dynamically modulated by SPIN90 phosphorylation that is dependent on cell adhesion and ERK activation PMID: 14559906
    7. SPIN90 participates in reorganization of the actin cytoskeleton and in actin-based cell motility PMID: 16253999
    8. These observations point to a pivotal role for DIP in the control of nonbranched and branched actin-filament assembly that is mediated by Diaphanous-related formins and activators of Arp2/3, respectively. PMID: 17398099
    9. DIP binds to and inhibits actin assembly by the FH2 domain of the formin mDia2 PMID: 17398099

    顯示更多

    收起更多

  • 相關疾病：
    A chromosomal aberration involving NCKIPSD/AF3p21 is found in therapy-related leukemia. Translocation t(3;11)(p21;q23) with KMT2A/MLL1.
  • 亞細胞定位：
    Nucleus. Note=Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.
  • 組織特異性：
    Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen.
  • 數據庫鏈接：

    HGNC: 15486

    OMIM: 606671

    KEGG: hsa:51517

    STRING: 9606.ENSP00000294129

    UniGene: Hs.655006



主站蜘蛛池模板： 色婷婷我要去我去也| 免费久久99精品国产自在现线| 色翁荡熄又大又硬又粗又动态图| 人人澡超碰碰97碰碰碰| 国产真实野战在线视频| 乱色国内精品视频在线| а天堂中文在线官网在线 | 97成人精品国语自产拍| 国产饥渴孕妇在线播放| 欧美成人国产精品高潮| 天堂√在线中文官网在线| 欧美乱大交av片久久123| 国产成人综合一区人人| 国产午夜福利精品久久2021| 天堂中文最新版在线中文| a在线亚洲男人的天堂| 久久99热只有频精品8| 精品久久人妻av中文字幕| 成人精品一区二区三区中文字幕| 亚洲一区二区制服在线| 久久97超碰色中文字幕蜜芽| 国产成人精品亚洲日本在线| 亚洲国产精品无码专区| 亚洲精品伦理熟女国产一区二区| 日韩人妻无码精品-专区| 国产乱妇乱子视频在播放| 最新精品视频2019在线视频| 日韩亚洲国产中文永久| 欧美牲交40_50a欧美牲交aⅴ| 女邻居的大乳中文字幕| 亚洲性人人天天夜夜摸18禁止| 久久大香国产成人av| 午夜精品久久久久久中宇| 欧美黑人异族videos| 日韩欧美激情兽交| 胸大美女又黄的网站| 国产区精品系列在线观看| 亚洲熟妇无码八v在线播放| 天天爱天天做狠狠久久做| 一本色道久久综合狠狠躁| 国产日韩在线视看高清视频手机|