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  4. NAV1 Antibody

NAV1 Antibody

  • 中文名稱：
    NAV1兔多克隆抗體
  • 貨號：
    CSB-PA070186
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    NAV1 antibody; KIAA1151 antibody; KIAA1213 antibody; POMFIL3 antibody; STEERIN1Neuron navigator 1 antibody; Pore membrane and/or filament-interacting-like protein 3 antibody; Steerin-1 antibody; Unc-53 homolog 1 antibody; unc53H1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Neuron Navigator 1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May be involved in neuronal migration.
  • 基因功能參考文獻：
    1. The +TIP Navigator 1 (NAV1) is important for neurite outgrowth and interacts and colocalizes with TRIO, a Rho guanine nucleotide exchange factor that enables neurite outgrowth by activating the Rho GTPases Rac1 and RhoG. PMID: 25065758
    2. NAV1 forms a complex with the RhoGEF TRIO and the +TIP EB1 on the plus ends of growing microtubules, and regulates TRIO-mediated Rac1 activation and neurite outgrowth. PMID: 25065758
    3. cloning of the gene neuron navigator-1 (NAV1), a human homolog of unc-53, a gene involved in axon guidance in Caenorhabditis elegans PMID: 12079279
  • 亞細胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Nav/unc-53 family
  • 組織特異性：
    Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15989

    OMIM: 611628

    KEGG: hsa:89796

    STRING: 9606.ENSP00000356265

    UniGene: Hs.585374



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