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NARFL Antibody

  • 中文名稱：
    NARFL兔多克隆抗體
  • 貨號：
    CSB-PA160212
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from A549 cells, using NARFL antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NARFL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NARFL
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from internal of Human NARFL.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
  • 基因功能參考文獻：
    1. we concluded that the Ser161Ile mutant induced NARFL deficiency and eventually diffuse PAVMs probably through VEGF pathway. In a word, we detected a functional mutation in NARFL, which might be the pathogenic gene in this pedigree. PMID: 27835862
    2. IOP1 is involved in mammalian cytosolic Fe-S protein maturation. PMID: 18270200
    3. human IscA1 plays an important role in both mitochondrial and cytosolic iron-sulfur cluster biogenesis, and a notable component of the latter is the interaction between IscA1 and IOP1. PMID: 19864422
  • 蛋白家族：
    NARF family
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 14179

    OMIM: 611118

    KEGG: hsa:64428

    STRING: 9606.ENSP00000251588

    UniGene: Hs.513247



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