在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NAGPA Antibody, FITC conjugated

NAGPA Antibody, FITC conjugated

  • 中文名稱：
    NAGPA兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA015417LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NAGPA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NAGPA
  • 別名：
    Mannose 6-phosphate-uncovering enzyme antibody; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase antibody; NAGPA antibody; NAGPA_HUMAN antibody; Phosphodiester alpha-GlcNAcase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase protein (327-438AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N-acetylglucosaminyltransferases.
  • 基因功能參考文獻：
    1. 14 variations were found in GNPTAB, GNPTG and NAGPA genes. PMID: 29289611
    2. SNPs covering GNPTAB, GNPTG and NAGPA were subjected to genotyping, association analysis was performed on all SNPs. Significant association of rs17031962 in GNPTAB and rs882294 in NAGPA with developmental dyslexia in a Chinese population was identified after false discovery rate correction for multiple comparisons. PMID: 25643770
    3. Mutational analysis of several residues in a highly conserved surface cavity of hUCE revealed that they are essential for function. PMID: 23572527
    4. To date mutations in GNPTAB, GNPTG, and NAGPA have been associated with stuttering. These genes encode the lysosomal enzyme targeting pathway, defective in mucolipidosis. (Review) PMID: 22884963
    5. Analysis of mannose 6-phosphate uncovering enzyme mutations associated with persistent stuttering. PMID: 21956109
    6. identified three mutations in the NAGPA gene associated with stuttering PMID: 20147709
    7. synthesis as a proenzyme that is activated by furin [mannose 6-phosphate-uncovering enzyme] PMID: 12058031
    8. The mannose 6-phosphate uncovering enzyme participates in the uncovering of the mannose 6-phosphate recognition tag on lysosomal enzymes, a process that facilitates recognition of those enzymes by mannose 6-phosphate receptors to delivery to lysosomes. PMID: 15976452

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Defects in NAGPA have been suggested to play a role in susceptibility to persistent stuttering. Stuttering is a common speech disorder characterized by repetitions, prolongations, and interruptions in the flow of speech.
  • 亞細胞定位：
    Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Note=Cis/medial Golgi.
  • 組織特異性：
    Isoform 2 may be brain-specific.
  • 數據庫鏈接：

    HGNC: 17378

    OMIM: 607985

    KEGG: hsa:51172

    STRING: 9606.ENSP00000310998

    UniGene: Hs.21334



主站蜘蛛池模板： 国产乡下妇女做爰| 亚洲人禽杂交av片久久| 国产成人av国语在线观看| 国产高清一区二区三区直播| 国产美女久久久亚洲综合| 激情五月婷婷| 国产综合精品一区二区三区 | 国产熟妇高潮呻吟喷水| 日韩av第一页在线播放| 日本无码一区二区三区不卡免费| 精品人妻少妇一区二区三区| 国产真人做爰毛片视频直播| 亚洲色欲久久久久综合网| 亚洲成av人片无码bt种子下载| 五月综合色婷婷在线观看| 2022国产日产欧产精品| 日本免费一区二区三区视频观看 | 玖玖玖国产精品视频| 他用舌头给我高潮喷水在线| 正在播放国产剧情亂倫| 日本三级吃奶头添泬无码苍井空| 人妻无码中文字幕免费视频蜜桃 | 亚洲一区二区三区自拍天堂| 国产精品无码av一区二区三区| 亚洲无线码在线一区观看 | 亚洲www啪成人一区二区麻豆| 亚洲精品无码mv在线观看| 亚洲亚洲人成无码网www| a三级三级成人网站在线视频 | 日本中文字幕有码在线视频| 7m精品福利视频导航| 国产欧美在线一区二区三| 国产大量精品视频网站| 人妻精品久久久久中文字幕69| 日本中文字幕有码在线视频| 国产a三级久久精品| 久久只有这里有精品4| 国产精品美女久久久久av爽| 欧美激情肉欲高潮视频| 2021精品国夜夜天天拍拍| 亚洲国产成人久久综合碰碰|