在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

N6AMT1 Antibody

  • 中文名稱:
    N6AMT1兔多克隆抗體
  • 貨號:
    CSB-PA010286GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    N6AMT1
  • 別名:
    N6AMT1 antibody; C21orf127 antibody; HEMK2 antibody; PRED28 antibody; Methyltransferase N6AMT1 antibody; HemK methyltransferase family member 2 antibody; M.HsaHemK2P antibody; Methylarsonite methyltransferase N6AMT1 antibody; EC 2.1.1.- antibody; N(6)-adenine-specific DNA methyltransferase 1 antibody; EC 2.1.1.72 antibody; Protein N(5)-glutamine methyltransferase antibody; EC 2.1.1.- antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human N6AMT1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Methyltransferase that can methylate proteins and, to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid. It however only plays a limited role in arsenic metabolism compared with AS3MT.
  • 基因功能參考文獻:
    1. combined effect of N6AMT1 haplotype 2_GGCCAT and As3MT haplotype 2_GCAC showed consistence with the additive significance of each haplotype on % iAs: the mean was 5.47% and 9.36% for carriers with both and null haplotypes, respectively PMID: 27637898
    2. AS3MT and N6AMT1 polymorphisms and urinary arsenic metabolites (%iAs, %MMA, %DMA) in 722 subjects from an arsenic-cancer case-control study in a uniquely exposed area in northern Chile, were examined. PMID: 28640505
    3. Five N6AMT1 single nucleotide polymorphisms and two N6AMT1 haplotypes were significantly associated with the percentage of methylarsonic acid in urine, even after adjusting for arsenic (+3 oxidation state) methyltransferase haplotype. PMID: 23665909
    4. N6AMT1 converted monomethylarsonous acid to dimethylarsonic acid when overexpressed in UROtsa human urothelial cells. It is expressed in many human tissues at variable levels, supporting a potential participation in arsenic metabolism in vivo. PMID: 21193388
    5. The human HemK2 protein methylates human and yeast eRF1.eRF3.GTP in vitro, and that the methyltransferase catalytic subunit can complement the growth defect of yeast strains deleted for mtq2. PMID: 18539146

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Eukaryotic/archaeal PrmC-related family
  • 組織特異性:
    Widely expressed, with highest expression in parathyroid and pituitary glands, followed by adrenal gland and kidney, and lowest expression in leukocytes and mammary gland.
  • 數據庫鏈接:

    HGNC: 16021

    OMIM: 614553

    KEGG: hsa:29104

    STRING: 9606.ENSP00000303584

    UniGene: Hs.163846



主站蜘蛛池模板: 日韩精品真人荷官无码| 国产乱子伦精品视频| 亚洲妇女水蜜桃av网网站| 亚洲精品国产一区二区三| 国产成人综合久久免费导航| 男人扒开女人腿桶到爽免费| 九月婷婷人人澡人人添人人爽| 亚洲乱码卡一卡二卡新区中国| 日本日本乱码伦专区| 熟女人妇 成熟妇女系列视频| 国产无遮挡又黄又爽又色| 久天啪天天久久99久久| 白嫩少妇bbw撒尿视频| 精品一区二区久久久久久久网站| 久久精品女人天堂av| 人人妻人人爽人人澡av| 久久国产精品_国产精品| 亚洲熟女乱综合一区二区| 无码少妇一区二区三区芒果 | 国产美女a做受大片观看| 强制高潮18xxxxhd日韩| 天堂www中文在线资源| 色哟哟网站在线观看| 亚洲成在人线a免费77777| 日韩人妻中文无码一区二区三区| 精品日本一区二区三区在线观看 | 97久章草在线视频播放| 色综合视频一区二区三区44| 久久妇女高潮喷水多| 中文乱码免费一区二区| 超清精品丝袜国产自在线拍| 国产日产韩国精品视频| 曰本女人与公拘交酡免费视频| 成人爽a毛片免费看| 国产精品无码午夜免费影院| 又粗又大又硬又长又爽| 亚洲性夜夜综合久久7777| 在线天堂资源www| 麻豆av福利av久久av| 在线aⅴ亚洲中文字幕| 国产人妻精品一区二区三首|