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Your Good Partner in Biology Research

  • 中文名稱:
    Mmp7兔多克隆抗體
  • 貨號(hào):
    CSB-PA014677EA01RA
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: Mmp7 antibody at 2µg/ml
      Lane 1: Colo320 whole cell lysaye
      Lane 2: NIH/3T3 whole cell lysaye
      Lane 3: Mouse lung tissue
      Lane 4: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 30 kDa
      Observed band size: 30 kDa
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Rattus norvegicus (Rat) Mmp7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Mmp7 antibody; Mmp-7Matrilysin antibody; EC 3.4.24.23 antibody; Matrin antibody; Matrix metalloproteinase-7 antibody; MMP-7 antibody; Pump-1 protease antibody; Uterine metalloproteinase antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Rat, Mouse, Human
  • 免疫原:
    Recombinant Rat Matrilysin protein (98-267AA)
  • 免疫原種屬:
    Rattus norvegicus (Rat)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,Mmp7 Antibody (CSB-PA014677EA01RA),的標(biāo)記方式是Non-conjugated。對(duì)于Mmp7 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA014677EB01RA Mmp7 Antibody, HRP conjugated ELISA
    FITC CSB-PA014677EC01RA Mmp7 Antibody, FITC conjugated
    Biotin CSB-PA014677ED01RA Mmp7 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
  • 基因功能參考文獻(xiàn):
    1. Placental ischemia, possibly through the release of TNF-alpha, causes increases in the levels of matrix metalloproteinase (MMP)-1 and MMP-7, which could alter collagen deposition and cause inadequate uteroplacental and vascular remodeling in hypertension in pregnancy. PMID: 28626073
    2. Expression of MMP-7, c-Jun and c-Fos were increased in skin photoaging. PMID: 23870463
    3. Increased extracellular nerve growth factor precursor levels following seizures are stabilized by altered MMP-7 enzymatic activity, leading to increased neuronal death via activation of p75(NTR). PMID: 22238106
    4. MMP-7 significantly contributes to intestinal epithelial wound closure. IL-1beta increased MMP-7 levels beyond those seen during normal healing. PMID: 20655064
    5. important role of MMP-2, MMP-9, and TIMP-4 in hypertensive remodeling of the cortex and medulla in the SHR rat PMID: 12923405
    6. Adrenergic alpha-agonist-induced activation of matrix metalloproteinase-7 promotes vasoconstriction through the epidermal growth factor-receptor pathway. PMID: 14656925
    7. MMP-7, which was produced by osteoclasts at the tumor-bone interface, was capable of processing RANKL to a soluble form that promoted osteoclast activation. PMID: 15894268
    8. Diminished expression of MMP-7 may play a role in fibronectin accumulation in the diabetic kidney in response to advanced glycation end products and/or TGF-beta. PMID: 17554258
    9. Claudin-7, kidney injury molecule-1 (Kim-1), and matrix metalloproteinase-7 (MMP-7) changed by aging and changes attenuated by caloric restriction. PMID: 17670906
    10. These results suggest a novel role for noncanonical WNT signaling in maintaining kidney transplant tolerance with MMP7 being a key target. PMID: 18209025
    11. MMP-7 cleaves the NR1 subunit of the N-methyl-d-aspartate (NMDA) receptor to generate an N-terminal fragment of approximately 65 kDa PMID: 18644839
    12. Agonist signaling of both hypertension and hypertrophy depends on posttranscriptional and transcriptional mechanisms that involve MMP-7, which is transcriptionally connected with ADAM-12 PMID: 19398663

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  • 亞細(xì)胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Peptidase M10A family
  • 數(shù)據(jù)庫(kù)鏈接:


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